Senior Director, Commercialization Technology Architect

## Senior Director, Commercialization Technology Architect Apply locations:
Boston, MAtime type:
Full time posted on:
Posted Todayjob requisition :
REQ-29730
** Job Description
**** Position Summary
** Vertex is entering an exciting phase of commercial diversification. As we expand into new pipeline disease areas and new geographies, we are investing in data, technology, and AI to scale commercial operations globally. The Commercial, Medical and External Affairs Technology team is expanding our capabilities with increased investment in data, platforms, and AI. This role establishes the end-to-end architecture required to scale AI and digital capabilities across the enterprise.

The
*** Senior Director, Commercialization Technology Architect
*** is responsible for defining and governing target-state architectures, integration patterns, and platform standards that enable scalable, secure, and compliant AI solutions. This role ensures technologies deployed by Product, Data, and Engineering teams are aligned to enterprise architecture, interoperable across systems, and built for long-term scale. This is a technical architecture leadership role focused on translating business and product direction into production-ready system design, data flows, and platform integration.
** Key Responsibilities
**** Architecture Strategy & Standards
*** Define and maintain target-state architecture across Commercial and Medical ecosystems
* Establish reference architectures, design patterns, and engineering standards for AI-enabled systems
* Govern architecture alignment across CRM, omnichannel, patient services, and enterprise platforms
* Ensure consistency with enterprise architecture and platform strategies
** Integration & Data Architecture
*** Own integration patterns and data flows across Salesforce, Veeva, data platforms, and downstream systems
* Define real-time and batch data architectures, including event-driven patterns and APIs
* Ensure alignment with enterprise data platforms (e.g., MDM, Snowflake, Databricks)
* Partner with Data teams to ensure data readiness, lineage, and interoperability
** Technology & Platform Governance
*** Partners with engineering function and core technology to define standards across cloud and data platforms MDM, Snowflake, Databricks, Snowflake supporting Commercial and Medical affairs domains
* Lead architecture decisions for build vs. buy vs. partner solutions
* Establish environment, deployment, and Dev Ops architecture patterns within the Commercial and Medical affairs domains
* Maintain architecture documentation for scalability, reuse, and audibility
** Security, Risk & Compliance
*** Ensure architectures meet SOX, GxP, privacy, and security requirements
* Define patterns for observability, audibility, and controls in AI systems
* Partner with Info Sec, Legal, Privacy, and Quality to embed compliance by design
** Delivery Enablement
*** Partner with Product Management, Engineering, and Data teams to translate product requirements into executable architectures
* Provide hands-on guidance to ensure solutions are production-ready and aligned to standards
* Serve as final architecture authority for design reviews and major platform decisions
** Knowledge & Skills
*** Deep expertise in enterprise architecture, solution design, and distributed systems
* Strong experience with CRM and commercial platforms (Salesforce, Veeva)
* Proven ability to design complex integrations and data architectures at scale
* Hands-on experience with cloud and data warehouse platforms (AWS, Azure, Snowflake, etc...) and modern data stacks
* Experience designing systems incorporating AI/ML and LLM-based capabilities
* Strong understanding of AI architectures (e.g. MCP)
* Expertise in security, compliance, and regulated environments (SOX, GxP)
* Ability to translate complex architecture into clear guidance for engineering teams
** Education & Experience
*** Bachelor’s or Master’s degree in Computer Science, Engineering, or related field
* 12+ years of experience in enterprise architecture or solution architecture roles
* Experience in pharma, biotech, or regulated healthcare environments strongly preferred
* Proven track record delivering…