IT Operations Manager

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Bicara Therapeutics is seeking a hands-on IT Operations Manager to lead and optimize our cloud and on-premises IT infrastructure and service desk operations. As the second IT hire, this role requires both technical expertise and leadership, balancing day-to-day IT operations, service management, and long-term IT growth strategy.

Reporting to the Head of Information Technology, the IT Operations Manager will be responsible for maintaining enterprise systems, managing IT service delivery, and ensuring a secure, efficient technology environment. Over time, this individual will play a key role in expanding the IT department, helping to define the technical roadmap and assisting IT leadership in growing the team. We are ideally seeking Massachusetts-based candidates who are able to work a hybrid schedule that includes 3 days per week in our Boston office.

Responsibilities:

IT Infrastructure & Hands-On System Administration

• Act as a technical lead while managing enterprise systems, network servers, and cloud environments.
• Be actively involved in troubleshooting, system upgrades, and automation efforts.
• Implement and manage tools for endpoint and mobile device management.
• Ensure robust data protection, disaster recovery, and failover processes.
• Automate and streamline IT processes, including onboarding/offboarding, ticket resolution, and infrastructure management.
• Manage IT vendor and SaaS relationships, including service providers for building IT, AV, and network design.
• Serve as the primary IT support resource, resolving escalated technical issues hands-on.
• Oversee end-user computing support across desktops, laptops, mobile devices, and cloud applications.
• Develop IT operational standards, including Service Level Agreements (SLAs), Incident, Problem, Change, and Knowledge Management processes.
• Establish documentation, training programs, and best practices to enhance technical knowledge and user support.

Security & Compliance

• Ensure compliance with SOX, GITC, and GxP regulatory standards.
• Enforce security best practices, including access controls, data encryption, and endpoint protection.
• Identify and mitigate risks, manage IT change processes, and maintain a secure and resilient IT infrastructure.

Strategic Growth & IT Expansion

• Partner with the Head of IT to develop the long-term IT strategy and grow the IT department as the company scales.
• Assist in identifying staffing needs, hiring plans, and technical roadmaps to build a world-class IT team.
• Provide technical mentorship and leadership, ensuring IT solutions align with business needs.
• Lead IT projects, balancing strategic planning with hands-on execution.

Qualifications:

Required:

• 5+ years of hands-on IT experience in system administration, IT operations, and service desk management.
• Strong technical expertise in Windows/Linux servers, VMware, AWS, Office 365, and enterprise SaaS solutions.
• Hands-on experience with networking, cybersecurity, and infrastructure automation.
• Proficiency in Power Shell, Python, or other scripting languages for automation and Dev Ops tasks.
• Proven ability to manage IT vendors, SaaS providers, and service agreements.
• Strong leadership skills, with experience managing IT service delivery and end-user support.
• Excellent problem-solving, communication, and customer service skills.

Preferred:

• Industry certifications (e.g., AWS, Microsoft, Cisco, ITIL, Security+).
• Experience in biotech, pharmaceutical, or research-driven environments.
• Understanding of IT Service Management (ITSM) and ITIL frameworks.
• Experience with cloud security, Dev Ops methodologies, and infrastructure-as-code.

Company Overview

Bicara Therapeutics is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara’s lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR) directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-β). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF-β signaling within the tumor…