Senior Biostatistician II

Job Description General

Summary:

The Senior Biostatistician II will perform scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with guidance and mentoring on new and complex issues. The incumbent will complete assigned work in a resourceful manner and create alternative approaches to achieve desired results. The incumbent will develop a good knowledge of related disciplines while performing Biostatistics activities with a drug developer mindset.

Key

Duties and Responsibilities:

Within assigned area, designs, develops and executes the technical/statistical infrastructure for the conduct and evaluation of clinical trials, observational studies, or real world data (RWD) investigations, including related areas/activities. Participates in regular Study Execution Team (SET) team meetings as the functional representative. Works under supervision to author study Statistical Analysis Plans (SAPs), including table, figure, and listing (TFL) shells, and presentation to Statistical Review Forum (SRF).

Plans and conducts Cross-functional Data Review (xFDR) , Key Results Memo (KRM), and Data Dissemination Plan (DDP) in order to facilitate the review, summary, and dissemination of key study data/results. Collaborates with statistical programming and other functions to ensure timely delivery of TFLs with good quality. Provides input into programming specifications and review. Develops statistical section of protocols, including sample size estimates and randomization plan.

Contributes to clinical study reports (CSRs) and related processes. May author or co-author methodological or study-related publications and posters. Implements design and analysis methods at the study level and participates in SRF discussions of studies assigned to others. Contributes to departmental working group efforts on various technical and operational issues. Seeks guidance and mentoring on new and complex issues Completes assigned work in a resourceful manner and creates alternative approaches to achieve desired results if needed.

Develops a basic knowledge of related disciplines with a drug developer mindset. Knowledge and

Skills:

Competence with SAS and R statistical software Demonstrated understanding of statistical methods used in drug development Ability to show critical thinking with logical problem-solving Excellent written and verbal communication skills Excels in a team environment Collaborates well with non-statisticians

Education and Experience:

Ph.

D. or master's degree in Statistics or Biostatistics. Typically requires 3 years of experience for those with a master's degree or the equivalent combination of education and experience. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range: $132,200 - $198,200 Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

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