Logistics & Distribution Senior Manager

Job Summary

The Senior Manager of Cold Chain Logistics Process is responsible for leading the development and implementation of processes and procedures to ensure the success of cold chain logistics operations within Vertex Pharmaceuticals. This position requires close collaboration with logistics service providers, order management teams, quality assurance, packaging engineering, and other stakeholders to ensure adherence to regulatory guidelines and meet business needs.

The Senior Manager will be an integral member of the logistics team, working to develop a robust logistics network to support pipeline programs, evaluate and launch logistics and supply chain information systems, and manage all quality systems from open to closure.

• Develop and implement standard operating procedures and work instructions with global contract manufacturing organizations and logistics service providers to ensure product quality and business needs are met.
• Manage quality systems, including deviations, CAPAs, and change controls, from open to closure.
• Work with logistics leadership to develop a robust logistics network to support pipeline programs, including supplier qualification, shipping validation, and lane selection.
• Evaluate, build, and launch logistics and supply chain information systems in conjunction with the Supply Chain Process and Systems lead and GIS.
• Ensure shipment plans are on time and compliant by working with key stakeholders such as Technical Operations, Trade Compliance, QA, and Supply Chain Planning.
• Define, measure, and communicate key performance indicators and supportive metrics that track the effectiveness of logistics and distribution operations.
• Participate in quality exceptions and solve complex logistical issues, selecting modes of transport as necessary.
• Ensure compliance with regulations such as Good Distribution Practices.
• Lead process redesign workshops and manage process changes.
• Educate business users responsible for managing and operating business processes.
• Monitor, measure, and provide feedback on process performance.
• Facilitate process workshops that involve eliciting process requirements and liaising with users.
• Coordinate the development of SOWs and POs.
• Assume business process ownership of new capabilities as required.
• Review and/or implement changes to controlled documents as needed.
• Perform other duties as assigned.

• Direct experience managing logistics of Cell and Gene Therapy programs and short lead time cold chain operations.
• Familiarity managing logistics with a network of both internal and external (CDMO) manufacturing sites.
• Demonstrated ability to work effectively in a collaborative and fast‑paced team environment, including business leadership to build alignment.
• Excellent understanding of Good Distribution Practices in the Pharmaceutical Industry.
• Working knowledge of Trade Compliance requirements.
• Fluency and proficiency with standard logistics and distribution activities.
• In‑depth analytical skills, strong verbal and written communication skills.
• Highly skilled in data analysis, manipulation, and presentation, including software skills with Microsoft Excel, Word, PowerPoint, Visio, and Access.
• Strong understanding of ERP systems; knowledge of Oracle‑based systems a plus.

• Bachelor's degree in engineering, scientific, business or related discipline.
• MS in Engineering, Business Management, Information Technology, Financial Management, or a similar relevant field.
• Typically requires 6 years of experience or the equivalent combination of education and experience in logistics and distribution.

Pay Range: $128,600 – $192,800. The base salary will be based on factors such as skills, experience, and competencies. The role may also be eligible for an annual bonus and equity awards. Benefits include medical, dental, vision coverage; paid time off; educational assistance; commuting subsidy; 401(k) plan; charitable donation matching; and other inclusive, market‑leading benefits. The Senior Manager may also be eligible for overtime pay in accordance with federal and state requirements.

Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities.