Global Commercial Head, Weight Management

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We are passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring innovative ideas to life.

Respiratory & Immunology, part of AstraZeneca Bio Pharmaceuticals is a key disease area and growth driver to the Company.

Our ambition is to improve and save lives for the millions of people who are living with the complexities of Cardiovascular, Renal & Metabolic (CVRM) diseases. AstraZeneca is uniquely positioned to improve the outcomes of patients living with CVRM diseases today and tomorrow with our strong and expanding portfolio and one of the broadest, deepest, most innovative pipelines in the industry.

By 2032, we intend to be leading the world in CVRM therapies, launching up to 15 new life-changing medicines.

To support this ambition, we are seeking a Global Commercial Head, Weight Management, a high-impact, global leadership role responsible for shaping and delivering commercial strategy across our Weight Management portfolio. This individual will play a critical role in defining the future of the category, enabling successful global launches, and driving long-term brand and portfolio value.

• Shape clear, actionable, winning commercial strategies across multiple assets and indications in the Weight Management portfolio.
• Lead development of integrated global commercial strategies, including pre-launch, launch, and lifecycle planning
• Develop and execute strategic and operational plans covering positioning, segmentation, pricing, value proposition, and target market prioritization
• Represent the global commercial perspective to inform clinical development, regulatory strategy, and lifecycle decisions
• Lead cross-functional global teams to deliver differentiated target product profiles and maximize asset value
• Drive forecasting, business case development, and performance tracking to inform decision‑making and portfolio prioritization
• Partner closely with regional and market organizations to ensure alignment from global strategy through to local execution
• Collaborate with Medical, Market Access, Regulatory, R&D, and other key functions to ensure compliant and impactful delivery of commercial plans
• Build strong relationships with external stakeholders including key opinion leaders, advocacy groups, and industry partners
• Lead and develop a high‑performing global team, fostering innovation, accountability, and talent development aligned to AstraZeneca values

• Bachelor’s degree in business, life sciences, or related field
• 10+ years experience in the pharmaceutical, biotechnology, or healthcare industry
• Demonstrated success in global or US commercial leadership roles, including launch experience
• Proven track record developing and executing brand or therapeutic area strategies grounded in customer and market insights
• Experience leveraging clinical data to inform strategy and lifecycle planning
• Strong leadership capabilities with experience managing cross‑functional and global teams
• Ability to influence senior stakeholders and drive alignment across complex organizations

• Advanced degree (e.g., MBA, PhD, or MD)
• Experience in CVRM and/or Weight Management
• Strong understanding of global healthcare systems, pricing, and market access dynamics
• Experience with forecasting, financial planning, and business case development
• Demonstrated ability to identify innovative, high‑impact strategies and deliver results
• High learning agility, strategic mindset, and strong communication skills

This position is based at our Boston, MA campus. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from…