Senior Manager, Program Management

Job Description:

Company Overview

Founded over a decade ago,CRISPR Therapeutic sis a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY®(exagamglogene autotemcel (exa-cel)), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia.

CRISPR Therapeutic sis advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact,CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including

Vertex Pharmaceuticals.

CRISPR Therapeutics AGis headquartered inZug,Switzerland, with its wholly-ownedU.S.subsidiary,CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco,California.

Position Summary

The successful candidate will play a critical role in achieving outcomes for our R&D programs. This person will join a strong program management team in the Boston, MA facility driving the success of R&D development teams. The individual will work collaboratively with the program teams and will manage and integrate the diverse drug development activities in key areas that include discovery, preclinical research, CMC and clinical manufacturing, regulatory affairs, clinical development, commercial, program strategy and finance.

This is an exciting and interdisciplinary role for a highly qualified and motivated individual. The successful candidate will be a confident program manager, with attention to detail and significant prior success in preclinical and early clinical stage program management for therapeutic programs in the biotechnology industry. The ideal candidate will be detail driven and have a proven track record in managing and driving program success.

The successful candidate will also have a solid scientific understanding of the biology of genome editing technologies, as well as the development of cell and gene therapies. We are seeking someone with a sense of urgency for developing important new therapies for devastating diseases and who is interested in forging new and uncharted paths for patients with the exciting CRISPR technology.

Responsibilities

• Drives program team(s) and is responsible for working closely with Program Leader and program team members to manage the operational aspects of the program(s), including developing overall strategy, tactical implementation plans, fully integrated program plan and timelines, and monitoring key milestones and decision points to drive delivery of program objectives
• Drives team objective setting, prioritization, and tracking ensuring adherence to plan and strategy
• Ensures cross-functional alignment and organizational support for the program plan and timelines by facilitating internal and external stakeholder management
• Implements project plan flawlessly; optimizes and tracks progress of project plans (time, resources)
• Interfaces and coordinates with relevant functional groups to ensure timely execution of program activities including anticipating and identifying program risks, mitigations and contingencies, and supporting timely action plans and issue resolution
• Drives issue identification and resolution and leads contingency planning for program team
• Ensures effective, proactive, and open communications, horizontally and vertically, in order to achieve transparency and clarity of program goals, progress, and issues, and, where necessary, engages line function management, other internal stakeholders and external experts to overcome obstacles
• Represents program to Senior Management; ensures effective communication to align program activities with corporate strategy, and ensure effective program execution
• Identifies and resolves conflicts at program team and functional team level
• Fosters a culture of ownership and single point of accountability with clear timelines, as well as ongoing evaluation, recognition and process improvement
• Is attuned to team dynamics and focuses on team needs directly and/or in partnership with other organizational leaders to ensure optimal team effectiveness
• Focuses operations to deliver results by influencing team members beyond existing benchmarks and their own expectations
• Leads ad-hoc cross-functional task forces and day-to-day operations of program team
• Ensures the development and use of key program management tools including GANTT charts, and the use of management logistics and documentation, by all team members, to enhance program delivery and…