Senior Director, Commercial Effectiveness

About Zevra Therapeutics, Inc.

We are a rare disease therapeutics company leading with science to make life-changing therapeutics available to patients with significant unmet needs. We involve key thought leaders, physicians, patients, care partners, and advocacy groups in all of our clinical and regulatory development strategies.

With a keen understanding that drug development often requires creative solutions, we have the insight and expertise to forge new pathways to success that others have missed. By following the data without bias, our transparent narratives and common-sense perspective have successfully overcome complex development challenges to make much-needed therapies available to patients.

Nimble and dauntless, we push boundaries beyond what is thought to be possible and advance new therapies that have the potential to bring meaningful improvement to patients’ lives.

About the role

Reporting to the Chief Commercial Officer, the Senior Director, Commercial Effectiveness is a strategic operator and enterprise integrator for the commercial organization. The role leads commercial effectiveness while enabling the Chief Commercial Officer to maintain focus on the highest-value priorities, decisions, relationships, and business outcomes. The role combines commercial effectiveness leadership, project and business performance management, and organizational accountability. It coordinates incentive compensation, congress planning, promotional and medical review operations, field effectiveness, CRM and commercial technology enhancements, vendor management, and appropriate budgeting.

Key Responsibilities

Congress Planning and Execution

• Coordinate cross-functional congress planning with Sales, Marketing, Medical Affairs, Market Access, Patient Advocacy, Legal, Regulatory, and Compliance.
• Oversee sponsor ships, exhibits, promotional activities, materials, logistics, agency support, shipments, expense processes, and post-congress reporting.
• Lead development of the annual commercial congress strategy across national and regional meetings.
• Establish congress prioritization, participation models, budgets, staffing plans and measures of success.

Promotional and Medical Review Operations

• Provide operational leadership for Promotional Review Committee and Medical Review Committee processes, including intake, prioritization, scheduling, routing, review meetings and approvals.
• Partner with Legal, Regulatory and Medical Affairs to maintain efficient, consistent, and compliant review practices.
• Establish service levels and performance metrics for review cycle time, first-pass quality, resubmissions, aging, bottlenecks, and on-time delivery.
• Oversee administration and continuous improvement of Veeva Promo Mats, Med Comms, and related workflows.
• Ensure promotional labeling, copyediting, proofreading, version control, and materials management processes are clearly governed and executed

Incentive Sales Compensation and Field Force Alignment

• Lead the design, implementation, governance, and ongoing evaluation of incentive compensation plans for customer-facing commercial teams.
• Partner with Sales Leadership, Human Resources, Finance, Legal, and external vendors on incentive philosophy, performance measures, goal setting, payout and plan documentation.
• Oversee incentive calculations, quality control, quarterly reconciliations, reporting, and plan effectiveness reviews.
• Support field force sizing, deployment, territory alignment, workload assessment, and resource optimization.

Marketing Operations and Commercial Enablement

• Lead operational support for marketing execution, including project intake, agency…