Contractor - Research Associate II, Protein Sciences

Ampersand Biomedicines is a Flagship Pioneering company on a mission to transform patients’ lives with programmed medicines that work precisely where needed, and nowhere else. We’re building a collaborative, mission-driven team that thrives in a fast-paced environment and shares a genuine desire to make a difference. We ACT our values by working with agility to adapt and deliver impact, leading with compassion to put people first, and practicing transparency to build trust through openness, clarity, and integrity.

At Ampersand, employees are encouraged to explore breakthrough science, take chances, support one another, and contribute ideas and perspectives openly.

Ampersand is currently seeking a highly motivated, passionate, and detail-oriented Research Associate I/II to join our Protein Sciences team. This is a bench facing role and you will be responsible for performing experiments, analyzing data, and presenting data to your supervisor and to cross-functional team in an effective and timely manner. The ideal candidate will have hands‑on experience working with mammalian cell culture, protein expression, purification and analytical QC using diverse biochemical methods such as ELISA, SDS‑PAGE, Western blotting.

This is a unique opportunity wherein the candidate will be responsible to assist multiple novel research projects along with in vitro and in vivo mAb discovery campaigns. The candidate is expected to have strong organizational, interpersonal, verbal, and written communication skills which will enable them to integrate with our highly cross‑functional team.

• Express and purify recombinant proteins from mammalian cultures.
• Routinely perform molecular biology techniques such as PCR, plasmid DNA preparation and bacterial transformation.
• Execute small- and large-scale protein purifications using immobilized metal affinity, ion‑exchange, and size exclusion chromatography.
• Characterize recombinant proteins using SDS‑PAGE, WB, protein quantitation, HPLC, ELISA and other biochemical/biophysical assays such as BLI and SPR to determine protein purity and function.
• Capture primary data and document work as required in Electronic Laboratory Notebook (ELN), maintaining up-to-date records.
• Present data routinely to the Protein Sciences group and other Ampersand teams.

• BS/MS in Biochemistry, Biomedical engineering, or related field.
• 0-2 years of academic or biotech/pharma laboratory experience is desirable.
• Strong organizational and communication skills along with excellent attention to detail is a must.
• Enjoys working in a collaborative, fast-paced and quickly changing environment.

• Experience with recombinant protein expression and purification using mammalian cell lines is preferred.
• Experience with FPLC systems and with affinity, IEX and SEC protein purification methods is preferred.
• Experience with general in vitro cell culture techniques is preferred.

Ampersand Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies:
Ampersand Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Ampersand and/or Flagship Pioneering or its employees is strictly prohibited unless contacted directly by Ampersand or Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Ampersand and FSP, and Ampersand/FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $36.00 - $45.00 hourly. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience.