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Pharmacology Senior Research Associate

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Vertex Pharmaceuticals Incorporated
Full Time position
Listed on 2026-05-30
Job specializations:
  • Research/Development
    Research Scientist
Salary/Wage Range or Industry Benchmark: 76100 - 114100 USD Yearly USD 76100.00 114100.00 YEAR
Job Description & How to Apply Below

Job Description General Summary

The Pharmacology Senior Research Associate conducts independent research to evaluate the effects of compounds on in vivo disease biology, with a strong emphasis on in vivo pharmacology and surgical execution in rodent models. This role requires excellent technical skills, strong attention to detail, and the ability to troubleshoot and adapt experimental approaches.

The ideal candidate will have hands‑on experience with rodent surgical procedures, including kidney‑related surgeries such as renal pelvis injection, and a strong understanding of kidney anatomy. Large animal in vivo surgical experience is a plus. This individual should demonstrate strong in vivo technical expertise, scientific rigor, and the ability to generate high‑quality data in a collaborative research environment. In addition to technical strength, the successful candidate will bring a strong team‑oriented mindset, a positive, can‑do attitude, and a willingness to support team and project goals.

Key

Duties and Responsibilities
  • Execute and interpret in vivo experiments with a high level of reliability, independence, and scientific rigor
  • Perform and support in vivo pharmacology studies, primarily in rodent models
  • Conduct rodent surgical procedures with strong technical proficiency, including kidney surgeries such as renal pelvis injection
  • Apply knowledge of kidney anatomy to support study planning, surgical execution, tissue collection, and data interpretation
  • Perform core in vivo procedures, including:
    • Animal handling
    • Dosing via multiple routes of administration (ROAs)
    • Blood and other fluid sample collection
    • Perfusion, necropsy, tissue dissection, and tissue processing
  • Contribute to experimental planning and support prioritization of studies based on project impact
  • Perform basic statistical analyses, as appropriate
  • Routinely troubleshoot experiments and refine methods to improve study outcomes
  • Prepare clear protocols, surgical procedures, and written study reports
  • Maintain awareness of relevant scientific literature, technical advances, and disease area trends
  • Present study results clearly and effectively at internal meetings
  • Work collaboratively across teams and contribute positively to a highly interactive research environment
  • Perform additional duties as assigned
Knowledge and Skills
  • Strong hands‑on experience in in vivo pharmacology, with demonstrated success in rodent studies
  • Proven technical expertise in rodent surgical procedures, particularly kidney surgery, including renal pelvis injection
  • Strong understanding of kidney anatomy and its application to experimental design, surgical procedures, and tissue evaluation
  • Experience with a broad range of in vivo techniques, including animal handling, dosing via multiple ROAs, perfusion, fluid collection, and tissue dissection/processing
  • Large animal in vivo and/or surgical experience is a plus
  • Strong analytical and problem‑solving abilities, including data interpretation and protocol refinement
  • Consistent reliability in experimental execution, data quality, and study delivery
  • Effective written and verbal communication skills
  • Strong teamwork spirit, a collaborative mindset, and a can‑do attitude
  • Developing knowledge of related scientific disciplines
Education and Experience
  • Bachelor's degree in a biological science required
  • Typically requires:
    • Bachelor's degree with 4+ years of experience, or
    • Master's degree with 0–2 years of experience, or equivalent combination of education and experience
Pay Range

$76,100 - $114,100

Disclosures

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing…

Position Requirements
10+ Years work experience
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