Scientist, In Vivo Pharmacology

Job Description

The Quantitative Biosciences Department at our Company's Research Laboratories is seeking a highly motivated Scientist to join our In‑Vivo Pharmacology group in Boston. The successful candidate will develop disease models, plan, design, and execute in‑vivo pharmacologic or mechanistic studies using disease models, collect and analyze data, and write reports to support R&D programs in immunology and oncology therapeutic areas.

• Plan, design and execute in‑vivo pharmacological experiments to support and advance drug discovery programs in immunology and oncology.
• Characterize and optimize in vitro, ex vivo or in vivo assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.
• Run validation and research operating plan (ROP) assays for test articles with appropriate benchmarks.
• Maintain timely, accurate laboratory records and comply with good documentation practices.
• Collaborate effectively with integrated teams in a matrix organization to facilitate studies and contribute to discovery programs.

M.S. in Immunology, Pharmacology, Biology, Biotechnology, Molecular and Cell Biology, Biochemistry, Bioengineering, or related STEM field with 1 + year of relevant postgraduate experience, or B.S. with 3 + years of relevant post‑graduate in‑vivo experience, preferably in a pharmaceutical or research laboratory setting.

• Hands‑on experience with in‑vivo models—particularly autoimmune disease or tumor immunology.
• Experience in PK/PD models, autoimmune/tumor efficacy.
• Skills in ELISA, Western blot, flow cytometry and other immunological assays.
• Proficiency with data analysis tools such as Graph Pad Prism, Flow Jo and Microsoft Office.
• Excellent written and interpersonal communication skills; ability to collate results and present to stakeholders.
• Ability to work independently and collaboratively across departments.

Assay, Autoimmune Diseases, Cell‑Based Assays, Drug Discovery Process, Flow Cytometry, Immunoassays, Immunology, Inflammatory Diseases, In‑Vivo Pharmacology, Mouse Handling, Mouse Models, Oncology, Tumor Models

None specified.

Salary range: $98,000.00 – $. Eligible for annual bonus and long‑term incentive, if applicable. Comprehensive benefits package including medical, dental, vision, retirement (401(k)), paid holidays, vacation, and sick days.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

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