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Senior Research Associate - Throughput Cellular Pharmacology
Job in
Boston, Suffolk County, Massachusetts, 02298, USA
Listed on 2026-06-04
Listing for:
Monte Rosa Therapeutics Inc.
Full Time
position Listed on 2026-06-04
Job specializations:
-
Research/Development
Research Scientist, Biomedical Science, Drug Discovery
Job Description & How to Apply Below
Overview
Monte Rosa Therapeutics is seeking a motivated High Throughput Ceelular Assasy expert to contribute to our mission of eliminating disease-causing proteins through targeted protein degradation, an innovative approach that enables us to target proteins once considered undruggable. The ideal candidate will have strong expertise in developing high-throughput cellular assays for screening and compound profiling. You will join a fast-paced and innovative team environment that values teamwork, collaboration, and scientific rigor.
Responsibilities
* Culture a variety of cell lines and primary cells to develop and optimize high-throughput cellular assays to evaluate target engagement, degradation and pathway modulation
* Utilize automation system to execute cell-based screening and profiling campaigns
* Collaborate within a matrixed environment that integrates multiple functions to drive program decisions.
* Keep meticulous records of experiments on ELN.
Qualifications
* MS or Ph.D. with in Molecular Biology, Biochemistry, Biology, or related field.
* The Senior Research Associate II level will have 4-6 years of relevent industrial experience and a Scientist wiill pocess 1-2 years industrial exerience
* A thorough understanding of assay principles is required
* Hands-on experience developing and executing cellular assays for lead discovery and optimization is required. Relevant assay formats include NanoBRET, cellular HTRF, Alpha
LISA, HiBiT, and NanoBiT, Degradation Kinetics.
* Experience working in a drug discovery environment is preferred.
* Experience with compound screening formats, laboratory instrumentation and automation, data analysis and management is preferred.
* Strong collaborative mindset with the ability to thrive in a team-oriented setting.
* Ability to adapt effectively to rapidly approaching deadlines in a dynamic research environment.
* Excellent oral and written communication skills.
Position Requirements
10+ Years
work experience
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