Postdoctoral Research Fellow - Lyn Jones LabLab

The Jones Lab is developing next-generation covalent chemical biology in the objective of expanding the druggable proteome. We are seeking a highly motivated individual to join our collaborative research efforts as a Postdoctoral Research Fellow working on chemical biology projects directed towards the development of novel therapeutic modalities.

Based at Dana‑Farber Cancer Institute in Boston, the lab has access to state‑of‑the‑art facilities for chemistry, biophysics, biochemistry, structural biology, and mass spectrometry.

• Design and synthesize chemical probes for target validation and chemoproteomics studies.
• Help develop and apply biochemical, biophysical, and metabolic stability assays.
• Screen compounds; analyze and interpret data.
• Apply data to the iterative design of optimized chemical probes suitable for cellular and in vivo pharmacological studies.
• Maintain accurate lab records and documentation.
• Contribute to publications and grant proposals.
• Stay current with scientific advances in chemical biology and medicinal chemistry, and apply emerging techniques and insights to research.

• PhD degree in chemical biology or a related discipline.
• Strong background in synthetic organic chemistry to enable delivery of chemical probes.
• Expertise in chemical biology techniques used to assess interactions between proteins and small molecules.
• Experience in biochemical/biophysical assay development.
• Excellent communication and presentation skills.
• Evidence of consistent scientific innovation with a proven track record of publications in peer‑reviewed journals.
• Able to work independently as well as in a collaborative team environment.
• Excellent organizational and prioritization skills with a strong attention to detail.
• Able to collect and analyze experimental data, prepare research publications, and communicate results.

Key salary range: $72,000.00 - $76,385.00

Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.