Associate Scientist , Nanoparticle Process Development Boston, Massachusetts

Associate Scientist I, Nanoparticle Process Development

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients. Strand was started by biological engineers working together at MIT, and its technology is therapeutic‑area and mRNA modality agnostic. The company has three platforms, one clinical‑stage asset (STX‑001) in phase 1, and several preclinical programs. Headquartered in Boston, Massachusetts.

Strand is looking for a highly motivated and innovative candidate for this role. The Associate Scientist I will support production and scale‑up of lipid nanoparticles (LNPs) with nucleic acid payloads, working under the Principal Scientist of Nanoparticle Process Development. The role requires strategic thinking, leadership presence, and depth in scientific knowledge.

• Execute experiments related to LNP mixing and downstream purification/filtration to improve the process.
• Contribute to the development of a robust formulation process with emphasis on scale‑up, tech‑transfer, and stability.
• Contribute to thorough characterization of LNPs by existing methods and collaborate with internal stakeholders on developing new methods.
• Coordinate with other team members to support the group’s research activities in a fast‑paced and collaborative environment.

• B.S. or advanced degree with at least 1‑2 years of relevant experience; educational focus in Chemical Engineering, Bioengineering or similar preferred.
• Experience with LNPs required; nucleic acid payloads highly preferred.
• Experience with TFF required; emphasis on LNPs preferred.
• Experience with QbD principles, scale‑up efforts and JMP DOE preferred.
• Experience with various mixing geometries and large‑scale LNP production preferred.
• Strong collaboration and interpersonal skills.
• Ability to multi‑task and prioritize to meet important deadlines.

Strand offers a fast‑paced, entrepreneurial, team‑focused small‑company environment and a top‑notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more). Work/life flexibility and integration are supported.

Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.

Job Type: Full‑time

Salary: $74,000 – $76,000 annually plus bonus and equity incentives