Associate Scientist

Title:

Scientist II (Associate)

Duration: 05+ Months Contract

Location:

Boston, MA 02115

Shift: Monday-Friday (8:00 AM to 5:00 PM) – 40 Hours/Week

• Support drug discovery programs through the design, development, and execution of cellular in vitro assays.
• Perform semi- and fully automated high-throughput screening of compounds and biologics.
• Conduct mammalian cell culture and cell-based assay activities in a research laboratory environment.
• Generate, analyze, and communicate experimental data to support research projects across multiple disease areas.
• Collaborate with multidisciplinary teams to advance therapeutic discovery and development efforts.

• Independently design and implement various cellular in vitro assays using a broad range of methodologies.
• Execute semi- and fully automated high-throughput compound and biologics screening assays.
• Develop and execute experimental strategies to define biomarkers, mechanisms of action, and resistance of therapeutic agents.
• Perform mammalian cell culture, passaging, harvesting, and cell-based assay execution.
• Run existing assays and contribute to assay development and optimization activities.
• Test compounds and evaluate biological activity in support of internal drug discovery programs.
• Properly document, analyze, and report experimental findings.
• Provide scientific contributions to research projects and programs across multiple therapeutic areas.
• Work collaboratively with scientists and cross‑functional teams to support projects at various stages of research and development.
• Utilize scientific software and statistical methods to analyze and interpret data.

Education:

• B.S./B.A. degree with a minimum of 3 years of relevant experience; OR
• M.S. degree with a minimum of 1 year of relevant experience.
• Bachelor's or Master's degree in Biology, Cell Biology, Molecular Biology, Biochemistry, or a related scientific discipline.
• PhD candidates are not being targeted for this role.

Experience:

• Extensive laboratory research experience in academic or industrial settings.
• Experience with medium- and high-throughput assay execution.
• Hands‑on experience with mammalian cell culture, passaging, and harvesting.
• Experience with cell‑based assays and assay development.
• Experience testing compounds in support of drug discovery programs.
• Experience with MSD and AlphaLISA/Alpha assays is preferred.
• Experience with assay troubleshooting and multiple high-throughput screening formats is a plus.

Skills:

• Mammalian cell culture techniques.
• Cell-based assay development and execution.
• High-throughput screening (HTS).
• Assay development and optimization.
  
  Data analysis and scientific problem-solving.
• Graph Pad Prism.
• PowerPoint.
• Basic statistical analysis including mean, standard deviation, and correlation analysis.
• Strong written and verbal communication skills.
• Ability to work independently and within multidisciplinary teams.