Postdoctoral Research Fellow - Anahtar Laboratory

Job Summary

Salary range: $70,000-$71,750.

The Anahtar Laboratory in the Division of Infectious Diseases at Massachusetts General Hospital is seeking a highly motivated, creative, and collaborative postdoctoral research fellow to join our team. Our lab combines machine learning, genomics, and experimental microbiology to address the growing crisis of antimicrobial resistance, with a particular focus on discovering new antibiotic candidates and developing next‑generation diagnostics for difficult‑to‑treat bacterial infections.

The hired candidate will focus on machine learning‑guided antibiotic discovery against pathogens of urgent clinical concern. We have developed and deployed deep learning models to identify structurally novel antibacterial hits against bacteria, with a focus on Neisseria gonorrhoeae. We have also applied generative AI approaches to design entirely new antibiotic scaffolds that explore uncharted regions of chemical space. We validate our computational discoveries through rigorous experimental follow‑up, including MIC testing across multidrug‑resistant clinical isolates, mechanism of action studies, and in vivo mouse infection models.

Our lab sits at the intersection of basic research and clinical translation. Our work is directly informed by the resistant organisms, diagnostic gaps, and treatment failures we encounter clinically. We collaborate closely with engineers, clinicians, biologists, and chemists across MGH, Harvard Medical School, the Broad Institute, and MIT.

Located in Boston, Massachusetts General Hospital is a Harvard Medical School‑affiliated academic medical center at the forefront of biomedical research and patient care. We are committed to building an inclusive, diverse, and equitable lab environment.

Recent graduates with a background in microbiology, chemistry, computer science, and/or immunology, a history of academic productivity, and excellent references are encouraged to apply.

Applicants should send the following:

• CV
• Cover letter describing background, research interests, and goals for post‑doctoral period
• PDF of a paper they have written

Please do not apply through this link. To apply, send materials to Melis Anahtar (du).

Remote Type

Onsite

Work Location

80 Blossom Street

1300 Massachusetts General Physicians Organization, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at .