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Principal Scientist - Formulation Development

Job in Boston, Suffolk County, Massachusetts, 02108, USA
Listing for: MRINetwork
Full Time position
Listed on 2026-07-01
Job specializations:
  • Research/Development
    Research Scientist, Pharmaceutical Science/ Research, Drug Discovery, Biotech Research
Job Description & How to Apply Below

Principal Scientist
- Formulation Development

Join our fast-paced biotech client specializing in the innovative field of orally delivered protein therapeutics. Be part of a groundbreaking team focused on transforming the future of medicine. We are actively searching for a dedicated Principal Scientist in Formulation Development to spearhead critical activities in oral delivery systems being developed for large molecule therapies. This is an exceptional opportunity to be part of a small multidisciplinary scientific team, working on various IND-enabling projects in a highly collaborative setting.

This position is hands-on, formulating and analyzing at the bench.

Qualifications for the Principal Scientist
- Formulation Development:

  • Ph.D. with 3-5 years of industry experience in Pharmaceutical Sciences, Biochemistry, Chemical Engineering, Biophysics, Bioengineering, Medicinal Chemistry, Polymer Chemistry, or Pharmaceutical Engineering.
  • Demonstrated expertise in developing oral delivery systems for biologics using diverse analytical methods.
  • Strong scientific ideation, statistical analysis, and design of experiments methodology.
  • Specialization in areas of oral peptides, oral proteins or delivery systems for biologics like robotic pills, LNPs (lipid nanoparticles) or TPEs (transient permeation enhancers)
  • Strong organizational skills and keen laboratory acumen.
  • Ability to work both independently and collaboratively within a multi-disciplinary team.
  • Proficiency in MS Office, Teams, SharePoint, and JMP.

Key Responsibilities of the Principal Scientist
- Formulation Development:

  • Formulation Leadership:
    Lead formulation development endeavors supporting multiple partner programs.
  • Method Development:
    Design and execute biologic oral delivery formulation techniques for drug product optimization.
  • Modeling and Testing:
    Develop scaled-down models and methodologies to evaluate drug product efficacy.
  • Innovation and Efficiency:
    Proactively identify avenues for improvements to achieve key business objectives.
  • Data Management:
    Generate and oversee protocols, data sets, and comprehensive reports.
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