Principal Scientist, Clinical Research - Immunology​/Dermatology

Overview

Clinical Director (Principal Scientist) has primary responsibility for strategic planning and directional oversight of clinical research activities involving investigational compounds in Immunology, with a focus on late‑stage development.

• Evaluate pre‑clinical and translational work to generate early clinical development plans and Investigational New Drug (IND) applications.
• Provide clinical development support for external business development opportunities to expand the Immunology pipeline.
• Develop clinical development strategies for investigational drugs and plan clinical trials (design, operational plans, settings) based on those strategies.
• Monitor and manage the conduct of ongoing or new clinical trials for investigational drugs.
• Analyze and summarize clinical findings to support decisions regarding safety, efficacy, new drug applications, clinical study reports, or publications.
• Participate in internal and joint internal/external research project teams relevant to new compound development.

• Supervise activities of Clinical Scientists in executing clinical studies.
• Work closely with cross‑functional experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects.
• Assist senior leadership and product development teams with progress updates, competitor analysis, and expert insights on scientific questions.

• Maintain awareness of scientific developments in Immunology, including new findings and research methodologies.
• Identify and engage scientifically and operationally strong investigators for development of company investigational drugs.
• Establish collaborative relationships with external experts in Rheumatology diseases whose expertise can inform drug evaluation.
• Attend relevant scientific meetings to maintain competency and awareness of research activities.

• Author detailed development documents, presentations, budgets, and position papers for internal and external audiences.
• Facilitate collaborations with external researchers worldwide.
• Travel on company business approximately 20 percent of the time to manage future or ongoing clinical research projects.

• M.D., D.O., M.D./PhD, or D.O./PhD

• Minimum of 5 years of clinical and/or development experience in academia, clinical medicine, or corporate clinical development.
• Demonstrated record of scientific scholarship and achievement.
• Preferred:
  Prior experience in design and execution of Phase 2 or Phase 3 clinical trials in rheumatologic diseases.
• Strong interpersonal skills and ability to collaborate effectively in cross‑functional teams.

• Allergy and Immunology
• Clinical Development
• Clinical Immunology
• Clinical Research
• Clinical Trials
• Dermatology
• Drug Investigation
• Immunology
• Statistics
• Strategic Planning

• Current employees and contingent workers may apply directly; please follow internal application procedures.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

Salary range: $ – $. The position may be eligible for an annual bonus and long‑term incentive, if applicable.

Benefits include medical, dental, vision, healthcare, and other insurance, retirement benefits (401(k)), paid holidays, vacation, and compassionate and sick days. For more information, please visit the company benefits page.

Applications can be submitted through the online portal. The Final date to receive applications will be indicated in the posting.

• Location:
  
  San Francisco (Resident Only)
• Travel Requirement: 10 percent
• Relocation:
  Domestic
• VISA Sponsorship:
  Yes
• Flexible Work Arrangements:
  Hybrid

For individuals residing in San Francisco or Los Angeles, the company will consider qualified applicants with arrest or conviction records in compliance with local fair chance ordinances.

Job posting end date: 07/27/2026.