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Bioanalytical Scientist, DMPK

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Commonwealth Sciences, Inc.
Contract position
Listed on 2026-07-14
Job specializations:
  • Research/Development
    Pharmaceutical Science/ Research, Biotech Research, Research Scientist, Drug Discovery
  • Pharmaceutical
    Pharmaceutical Science/ Research, Drug Discovery
Salary/Wage Range or Industry Benchmark: 120000 - 150000 USD Yearly USD 120000.00 150000.00 YEAR
Job Description & How to Apply Below
Position: Bioanalytical Scientist, DMPK (Contract)
  • Design, execute, and interpret biotransformation studies to characterize drug metabolites.
  • Conduct hands‑on laboratory work, including sample preparation, LC‑MS/MS, and high‑resolution mass spectrometry (HRMS) for metabolite profiling.
  • Oversee and manage outsourced studies with CROs, ensuring scientific quality and compliance with project timelines.
  • Provide detailed interpretation of metabolite data to guide medicinal chemistry and safety assessment decisions.
  • Develop, optimize, and validate innovative analytical methods to improve biotransformation workflows.
  • Author and review high‑quality scientific reports, regulatory submissions, and presentations.
  • Collaborate effectively with cross‑functional teams, including bioanalytical, toxicology and medicinal chemistry.
Requirements
  • PhD in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related discipline, with 3+ years of relevant industry experience.
  • Strong expertise in drug metabolism, with hands‑on experience using LC‑MS/MS.
  • Proficiency in GLP/GCP‑compliant laboratory regulations, ICH guidelines and procedures.
  • Familiarity with oligonucleotide biotransformation.
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