Associate Director, Computational Biology

Job Description

We have an exciting opportunity for an Associate Director / Director, Computational Biology Scientific Operations & Capability Lead to join the Computational Biology team within the Gastrointestinal & Inflammation Therapeutic Area Unit (GI2-TAU).

We are looking for:

• A scientific leader who will play a pivotal role in expanding Computational Biology capabilities and scientific impact across GI2 programs through high-quality external scientific execution, reusable analytical capabilities, and operational excellence.
• An expert in computational biology and translational bioinformatics with deep experience in multi-omics analysis, biomarker research, and AI/ML-enabled analytical approaches, capable of guiding and critically evaluating complex scientific analyses.
• A strategic collaborator who will partner with clinical development, translational medicine, discovery, and DD&T teams to ensure externally supported Computational Biology activities remain aligned with program priorities and portfolio needs.
• A capability builder and innovator who will establish scalable workflows, scientific standards, and best practices that improve consistency, quality, & reproducibility across Computational Biology activities.
• A scientific operations leader who will serve as the primary interface between the Boston-based Computational Biology team and India-based FSPs, contractors, and external scientific partners, reducing communication, coordination, and oversight burden while strengthening execution quality across the network.

ACCOUNTABILITIES (Describe the primary duties and responsibilities of the job. Include only the essential functions of the job. Approximately 5-10 bulleted task statements should be identified.)

• Serve as the primary scientific interface between the Boston-based Computational Biology team and India-based FSPs, contractors, and external partners.
• Translate GI2 scientific priorities into clear analytical plans, deliverables, and quality expectations.
• Oversee externally supported Computational Biology activities and reduce coordination and oversight burden on Boston-based scientists.

• Provide scientific leadership and oversight for Computational Biology analyses, ensuring outputs are rigorous, reproducible, and decision-ready.
• Apply expertise in computational biology, multi-omics, biomarkers, and translational research to guide analysis and interpretation.

• Build reusable Computational Biology workflows, standards, and best practices that can be applied across programs and disease areas.
• Advance scalable analytical capabilities through partnerships with Computational Biology, Digital, DD&T, and Data Science teams.

• Maintain targeted engagement with priority programs to ensure external execution remains aligned with scientific and portfolio priorities.
• Support program teams with insights related to biomarkers, disease biology, patient stratification, and multi-omics analysis.
• Foster a culture of scientific excellence, innovation, collaboration, and continuous improvement across internal and external teams.

• Deep expertise in Computational Biology, Bioinformatics, Systems Biology, Translational Bioinformatics, or related disciplines.
• Strong background in multi-omics analysis, biomarker discovery, patient stratification, and translational data analysis.
• Experience applying advanced analytical approaches, including AI/ML methods, to support decision-making.
• Ability to review, challenge, and guide complex scientific analyses and biological interpretations.
• Strong understanding of reproducible research practices, data quality standards, and analytical governance.

• Provide scientific leadership across internal and external teams within a matrix environment.
• Influence scientific strategy, operating models, and capability development initiatives.
• Drive alignment among diverse stakeholders with competing priorities.
• Build trust and credibility with scientific leaders, program teams, and external partners.

• Operate independently with broad accountability for quality and effectiveness of external Computational Biology execution.
• Make informed decisions regarding analytical approaches, prioritization, quality standards, and risk mitigation.
• Provide recommendations that influence program decisions, capability investments, and operational strategy.

• Collaborate across Computational Biology, Translational Medicine, Clinical Development, Discovery, Biomarker Sciences, and DD&T functions.
• Engage regularly with FSPs, contractors, CROs, academic collaborators, and technology partners.
• Communicate complex scientific concepts effectively to technical and non-technical audiences.

• Drive adoption of scalable analytical approaches and reusable Computational Biology capabilities.
• Champion continuous improvement, operational excellence, and…