Distinguished Scientist, Quantitative Biosciences​/ Nonclinical Pharmacology

Overview

We are committed to improving the health and well‑being of people around the world. As a leading global pharmaceutical company, we strive to make a difference through innovative research, discovery, and development of life‑saving medications and vaccines. With over a century of experience and a steadfast dedication to scientific excellence, we have become a trusted name in the industry. Join our team and be a part of our mission to create a healthier future for all.

• Serve as a scientific integrator, strategic partner, and chief‑of‑staff to the Vice President/ Global Department Head of Quantitative Biosciences and on the QB leadership team, shaping enterprise pharmacology & translational strategy in alignment with QB and DPTM priorities.
• Drive clarity and alignment on pharmacology strategies that enable efficient SAR progression and translational confidence—ensuring approaches are fit‑for‑purpose, decision‑focused, and avoid unnecessary complexity.
• Apply deep expertise in biochemical, cellular, and translational systems to:
  • Clarify mechanism‑of‑action & inform molecule differentiation at critical decision points
  • Guide fit‑for‑purpose assay and model strategies that streamline research operating plans (ROPs), and directly inform SAR and program progression
• Advise and mentor broadly across QB and DPTM
  , guiding scientists and multidisciplinary teams in assay selection/design/execution, mechanistic pharmacology, and translational science to accelerate programs, elevate rigor, and develop talent.
• Act as a trusted advisor on high‑impact and complex programs
  , helping teams resolve key scientific uncertainties and translating complex data into clear, actionable insights that inform strategic and program‑level decisions.
• Shape the QB pharmacology portfolio and resourcing strategy
  , contributing to early target and end‑to‑end nonclinical pharmacology planning across disease areas and modalities, and driving visibility through portfolio dashboards, resource planning, and stakeholder alignment.
• Assess and interpret the evolving external landscape
  , delivering actionable insights on competitive pipelines, emerging trends, and strategic opportunities through dashboards, analyses, and executive‑ready recommendations.
• Partner closely with Business Development & Licensing (BD&L) as a scientific leader in pharmacology and quantitative biosciences, supporting asset evaluations, due diligence, and opportunity assessments across modalities and stages of R&D.
• Foster a culture of scientific rigor, critical thinking, and open dialogue
  , strengthening decision‑making and elevating organizational capability.
• Promote a collaborative, inclusive, and high‑performing environment aligned with company values and mission.

• Bachelor's degree in pharmacology, biology, or a related discipline, with deep expertise in mechanistic pharmacology, drug discovery, and preclinical development across modalities (small molecules, biologics, vaccines).
• Advanced degree (Ph.D.) preferred.

• 15+ years of proven leadership in a biopharmaceutical setting, with extensive research experience and a demonstrated impact on drug discovery and translational programs. Experience in cardiometabolic disease, obesity, oncology, and/or immunology strongly preferred, with a track record reflected in publications and scientific reputation.
• Deep expertise across pharmacology disciplines, including biochemical/biophysical, cellular, and in vivo pharmacology, PK/PD, IVIVC, and translational science.
• Proven ability to simplify complex scientific challenges into clear, actionable strategies and to influence without authority across organizational boundaries to drive alignment, consistency, and high‑quality decision‑making.
• Strong executive communication and stakeholder engagement skills, with the ability to effectively partner with senior leaders, cross‑functional teams, and external collaborators.
• Demonstrated experience in business development and licensing, including competitive landscape assessment, industry analysis, and scientific support for transactions and due diligence.
• Track record of mentoring and…