Director or Senior Director, Translational Medicine Lead

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions.

Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit  or follow us onX (formerly Twitter) orLinked

In.

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions.

Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit  or follow us onX (formerly Twitter) orLinked

In.

• PIONEER:
  We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE:
  We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG:
  We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

• Serves as an Immunology Translational Medicine Program Lead on cross-functional project team(s) and develops translational medicine and biomarker strategies to support early and late phase clinical trials
• Collaborates with Medicine team to develop clinical trials in appropriate patient populations
• In partnership with the Translational Medicine Biomarker Operations team and Clinical Operations team oversees seamless implementation of translational assays in the clinic
• Develops and validates clinical assays at outsourced partner laboratories using multiple assay technology platforms (e.g., cell-based assays, molecular-based assays, single or multiplexed immunoassays, flow cytometry and/or imaging technologies)
• Ability to review and interpret data /results from multiple types of biomarker assays and integrate findings
• Presents translational medicine data packages internally and externally as required
• Effectively coordinates with Translational Medicine Biomarker Operations team to manage external collaborations with academic partners and CROs to deliver results on time and on budget
• Review and author translational medicine sections of clinical documentation, including clinical protocols, study reports, consent forms; abstracts and/or manuscripts and regulatory documents (e.g. IND, IB etc.)
• Builds biomarker knowledge base in the context of disease outcomes to contribute to advancement of clinical stage programs
• Monitors developing biomarker approaches and incorporate novel technologies in support of ongoing and new clinical programs
• Interfaces effectively with Translational Medicine Head to ensure alignment on topics

• PhD +8-10 years of experience in translational medicine/ science within the biotech/pharmaceutical industry
• Demonstrated success leading translational medicine efforts for immunology and /or respiratory drug development programs
• Demonstrated experience delivering high quality clinical biomarker data to inform decisions and development strategy
• Track record of…