Senior ​/ Staff Scientist, Neuromodulation

Senior / Staff Scientist Opportunity At Neuro Bionics

Neuro Bionics, an MIT neurotechnology spinout, is developing novel implantable devices that interface seamlessly with the human body to treat neurological conditions. Leveraging over a decade of innovation, we have engineered a novel neural interface using microscale, flexible, bioelectronic fibers that can be delivered into the body through minimally invasive endovascular approaches. By making neural interfacing a minimally invasive procedure, we aim to revolutionize deep brain stimulation and broaden access to life-changing neuromodulation therapies to millions of patients.

As the company's scientific expert on neuromodulation, you will set the scientific foundation for which targets we pursue and prove out our platform in vivo. Your work spans three connected areas: neuromodulation strategy and scientific diligence, preclinical animal studies, and — with external expert support — characterization of the chronic stability of the ev Fiber lead.

Neuromodulation Strategy & Scientific Diligence

• Serve as the in-house expert on neuromodulation targets, mechanisms, and what the literature actually supports — bringing deep neurobiology and neurophysiology expertise to every discussion.
• Reason from first principles of neurophysiology: nerve and tract anatomy, the function of specific targets, and how stimulation parameters (frequency, amplitude, pulse width, waveform) map to neural activation and downstream effects on nerves, muscles, and organ systems.
• Build and maintain deep, current knowledge of the neuromodulation landscape — which targets and indications the field is pursuing, the mechanism and physiology behind each, the competitive and clinical-trial activity underway, and where the evidence base is strong versus thin.
• Critically appraise the preclinical and clinical literature for candidate targets, assessing strength of evidence, translatability from animal models to humans, and which stimulation parameters drive which physiologic effects.
• Partner with our strategic marketing lead to evaluate candidate indications and neural targets, and help shape the company's target roadmap and indication pipeline.
• Track emerging data from ongoing clinical trials and the broader field, and translate those insights into our study design, stimulation paradigms, and strategic priorities.

Preclinical Animal Studies

• Design and implement in vivo animal studies testing the ev Fiber neuromodulation platform across multiple therapeutic targets (e.g., vagus nerve, peripheral nerves, deep brain targets).
• Develop evidence-based stimulation paradigms by reviewing the neuromodulation literature and define appropriate outcome measures and controls for each target and indication.
• Record, process, and analyze electrophysiology data and other physiologic endpoints (e.g., stimulation-evoked neural activity, cardiovascular responses, autonomic effects) to demonstrate neuromodulation efficacy.
• Perform quantitative data analysis and results visualization on electrophysiology time series and physiologic datasets; synthesize findings into clear scientific reports and presentations.
• Contribute to preclinical study reports and regulatory documentation in support of 510(k) or IDE submissions.
• Stay current with the neuromodulation literature across central and peripheral targets; identify relevant benchmarks and translate insights into study design and stimulation parameters.

Electrode & Lead Chronic Stability Characterization

Working closely with our expert external consultant in electrode materials science and electrochemical characterization, you will:

• Execute electrochemical characterization of the electrodes on the ev Fiber lead — including impedance spectroscopy, cyclic voltammetry, charge injection capacity, and charge storage capacity measurements — under the guidance of our external consultant.
• Assist in designing and running accelerated aging experiments to evaluate long-term electrode and lead stability; interpret results against FDA/ISO safety standards and Shannon charge injection limits.
• Help identify and characterize failure modes of the…