Associate Principal Scientist, In Vivo Pharmacology, Oncology
Listed on 2026-08-27
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Research/Development
Research Scientist, Medical Science, Clinical Research, Oncology Care
Associate Principal Scientist
Our Discovery Quantitative Biosciences (QB) In Vivo Pharmacology – Oncology team in Boston is searching for a collaborative and innovative Associate Principal Scientist with a strong background in Oncology In Vivo Pharmacology. The successful candidate will be an experienced In Vivo cancer biologist who will direct Oncology reverse-translational activities while serving as a key intellectual contributor in the conception and execution of Oncology drug discovery projects.
The role will involve building alliances with Discovery Oncology teams at the Boston and South San Francisco sites, championing new technologies, and interfacing with our global pharmacology network. The successful applicant will also have the skill sets to collaborate with teams in different functional areas (e.g., Bioinformatics, Discovery Chemistry, and Discovery Biologics) in a highly matrixed system and with external partners.
The successful candidate will:
Education:
- PhD in Oncology, Pharmacology, Biology, Pharmaceutical Sciences, Chemistry, Immunology, Biotechnology, Molecular and Cell Biology, or related STEM field with 5+ years of industry / biotech experience in Oncology drug discovery, or an MS with 7+ years of experience, or a BS with 10+ years of experience.
Required Skills:
- Experience using preclinical models to evaluate the in vivo pharmacology of novel modality-agnostic oncology drugs (small molecules, antibodies, ADCs, TCEs etc).
- Experience at managing external studies at CROs and academic collaborators including monitoring study execution and ensuring finalization of study reports within set timelines.
- Proven managerial/supervisory experience with a track record of training, developing talent, and mentoring team members in the field of Oncology/pharmacology and drug discovery.
- Proficiency in complex problem-solving and the ability to influence strategy across organizational boundaries.
- Strong skills in strategic thinking, effective communication, collaboration, balanced risk-taking, and a relentless pursuit of excellence.
Required Skills:
Immunoassays, Immunohistochemistry (IHC), Immunology, In Vivo Models, In Vivo Studies, Mass Spectrometry Imaging, Molecular Biology, Mouse Models, Multiplex Assays, Oncology, Pharmacodynamics, Pharmacokinetics, Pharmacology, Preclinical Research, Tumor Biology
Preferred
Skills:
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The salary range for this role is $ - $. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at (or via the Workday Jobs Hub if you are a current employee).
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