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Scientist, Bioscience Immunology

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: AstraZeneca
Full Time position
Listed on 2026-09-13
Job specializations:
  • Research/Development
    Immunology Research, Research Scientist
Salary/Wage Range or Industry Benchmark: 92252 - 138378 USD Yearly USD 92252.00 138378.00 YEAR
Job Description & How to Apply Below

Introduction to role

Are you driven to transform cutting-edge immunology into therapies that make a tangible difference for patients? Do you thrive in fast-moving scientific environments where not all the answers are known yet? Join a lab dedicated to discovering, validating, and advancing novel targets using human in vitro systems and primary and disease tissue-derived cells.

In this role, you will connect deep biological insight to decision-making in drug discovery. Working in state-of-the-art labs alongside accomplished scientists, you will characterize immune pathways in health and disease, design and optimize assays, and generate data that shape program strategy. Expect high visibility, cross-functional collaboration, and the opportunity to publish impactful work while building capabilities that accelerate medicines to patients.

Accountabilities
  • Immunology Pathway Characterization:
    Define and interrogate novel immunological pathways in autoimmune diseases to drive target validation and guide therapeutic hypotheses for drug projects.
  • Human In Vitro and Ex Vivo Models:
    Design, execute, and refine studies using primary and disease tissue-derived cells to generate translational data that inform program decisions.
  • Assay Development and Validation:
    Build, optimize, and qualify robust cellular, molecular, and protein assays; establish standards and controls to ensure reproducibility and decision-grade data.
  • Advanced Analytics and Data Integrity:
    Apply rigorous experimental design and statistical thinking to critically analyze complex datasets and communicate clear, actionable conclusions.
  • Cross-Functional Collaboration:

    Partner with project teams and external collaborators to align on goals, share insights, and accelerate progress; bring external science and technologies in when they create advantage.
  • Scientific Leadership and Publication:
    Lead aspects of the biology, contribute to strategy discussions, and publish high-quality research in reputable journals to advance the field and our pipeline.
  • Continuous Improvement in a Dynamic Environment:
    Navigate ambiguity with resilience; iterate quickly, learn from setbacks, and adopt inventive approaches that keep programs moving at pace.
Essential Skills/Experience
  • Master’s degree in biology, immunology or relevant discipline with 3+ years of relevant industry experience is required OR PhD degree in biology, immunology or relevant discipline with 0+ years of post-doctoral experience is required
  • Expertise in adaptive and innate immunity, primary cell culture and assay development is essential
  • Highly organized and self-motivated, with the ability to work independently as well as collaboratively within a team to conduct a high-level research project is essential
  • Strong hands‑on skills in establishing immunological screening assays, with demonstrated proficiency in several of the following: primary cell culture, multi‑panel flow cytometry (including both intracellular and extracellular markers), ELISA, Western blot, MSD, Luminex etc
  • Strong written and oral communication skills and the ability to critically analyze data sets
  • Demonstrated ability to run collaborative efforts and utilize external resources to find the most effective solutions
Desirable Skills/Experience
  • Previous experience in independently designing & optimizing biological screening assays in human cell lines, PBMCs, whole blood.
  • Experience with multiplex cytokine read‑outs and in vitro/ex vivo culture of immune cells.
  • Prior experience with screening and profiling small molecules and/or biologics in immune-based assays.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect,…

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