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Senior​/Principal Scientist, RNA DP

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Recipharm
Full Time position
Listed on 2026-10-05
Job specializations:
  • Research/Development
    Research Scientist, Pharmaceutical Science/ Research
Salary/Wage Range or Industry Benchmark: 145000 - 155000 USD Yearly USD 145000.00 155000.00 YEAR
Job Description & How to Apply Below
Job Summary

This position reports to the Head of Technical Operations and plays a key role in leading laboratory /experimental approaches for optimized RNA production. They will lead the efforts to design, execute, and interpret critical experiments for the success of various RNA modalities in activities including IVT high throughput screening, downstream development, process scale-up and tech transfer. This role will also support downstream process development for plasmid purification and related analytical development for in-process monitor and final product release.

The individual will work collaboratively in a cross-functional environment including analytics, tech transfer, GMP manufacturing and Quality. The successful candidate has a big potential to grow as a leader in nucleic acid process science group.

Essential Job Function
  • Serve as a scientific/laboratory leader to guide & mentor scientists and associates within RNA process science team
  • Serve as a Subject Matter Expert in RNA process to lead RNA process development activities in a combination of customer related, and internal related projects. These may include technology transfer, technology establishment, scale up manufacturing, process optimization, platform development.
  • Assist in plasmid downstream process development using related chromatography and filtration technologies.
  • Design & execute complex and technically challenging experiments for trouble shooting and method development.
  • Support leadership team to evaluate new technologies and lead internal/external technical collaborations.
  • Evaluate functional strengths and identify developmental areas with the ability to focus on continuous improvement
  • Represent plasmid process development in cross-functional team forums including GMP manufacturing/non-GMP manufacturing, interdepartmental meetings, etc.
  • Lead presentation, publication and/or patenting of findings or is a major contributor to these processes.
Experience And Skills
  • Experts with extensive hands‑on experience in production of mRNA, saRNA, siRNA, circRNA, and/or other RNA modalities.
  • Extensive hands‑on experience in process characterization and common RNA analytics.
  • Deep knowledge in IVT reaction optimization and mRNA downstream unit operations.
  • Experience with statistical design of experiments (DOE) is a plus.
  • Experience with commercial scale up, large‑scale bio‑manufacture and cGMP is a plus.
  • Ability to independently design experiments, analyze complex data and interpret and present experimental results, required.
PHYSICAL DEMANDS
  • While performing the duties of this job, the employee is frequently required to stand; sit; use hands to finger, handle, or feel; reach with hands and arms; and talk or hear.
  • The employee is occasionally required to walk; climb or balance; and stoop, kneel, crouch, or crawl.
  • The employee must frequently lift and/or move up to 10 pounds and occasionally lift and/or move up to 25 pounds.
  • Specific vision abilities required by this job include close vision, and ability to adjust focus.
  • In the performance of the duties of this job the employee is not required to travel
  • The employee will be required to communicate using telephone and e-mail.

Annual Base Salary Range from $145,000 to $155,000

Recipharm is a leading Contract Development and Manufacturing Organisation (CDMO) employing over 4,500 employees worldwide. Recipharm provides manufacturing services of pharmaceuticals in various dosage forms, including, sterile fill & finish, oral solid dosage and biologics; clinical trial material development and manufacturing services; and, pharmaceutical product development. Its biologics segment, Reci Bio Pharm , works with customers to develop and commercialise advanced therapy medicinal products (ATMPs): pre-clinical to clinical and commercial development and manufacture for new biological modalities, encompassing technologies based on live viruses and viral vectors, live-microbial biopharmaceutical products, nucleic acid‑based mRNA and plasmid DNA production.

Recipharm manufactures several hundred different products to customers ranging from big pharma to smaller research and development companies. It operates development and manufacturing facilities in France, Germany, India, Italy, Portugal, Spain, Sweden and the US and is headquartered in Stockholm, Sweden.

For more information on Recipharm and our services, please visit  and

Position Requirements
10+ Years work experience
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