Analytical Science and Technology Senior Scientist

General Summary

The Senior Scientist, Analytical Sciences & Technology (AS&T), plays a critical role in the Commercial Manufacturing & Supply Chain team. You will be responsible for providing strong expertise on analytical requirements to ensure launch readiness and lifecycle management for the commercial small molecule portfolio.

• Accountable for the success of commercial analytical activities, prioritization, and execution to meet program commitments.
• Subject Matter Expertise (SME) for ensuring the robustness of analytical methods, commercial testing requirements, and managing analytical event investigations.
• Author and/or review technical documents, including methods, study protocols and technical reports.
• Partner effectively with internal and external functions for commercial analytical technology transfer.
• Primary responsibilities extend to analytical method validations, continuous improvement, and lifecycle management.
• Collaborate with Vertex cross‑functions, including Analytical Development, Process Development, Commercial Manufacturing, Supply Chain, Quality teams, Vertex Partners, and Contract Test labs.
• Provides oversight for analytical testing and method performance executed at CDMOs and contract testing labs.

• Demonstrated expertise in analytical method development, characterization, and qualification/validation.
• Knowledgeable in ICH/FDA/EMA guidelines with a strong GMP background; small molecule related preferred.
• Experience managing contract (CMO/CDMO) analytical testing, highly desirable.
• Experience with technical support of commercial small molecule products and cGMP manufacturing.
• Ability to prioritize objectives from multiple projects and adhere to scheduled timelines while maintaining flexibility and efficiency.
• Excellent technical writing and communication skills, with a proven ability to build open and collaborative relationships.
• Hands‑on experience with methods related to small molecule products, preferably dissolution test.

• Bachelor’s degree or above in Science or a related discipline.
• 8 years of experience in the pharmaceutical/biopharmaceutical industry, or an equivalent combination of education and experience.

$120,000 - $180,000

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law.

Hybrid-Eligible Or On-Site Eligible

• Hybrid: work remotely up to two days per week; or
• On‑Site: work five days per week on‑site with ad hoc flexibility.

Note:

The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at A