Director, Discovery Oncology, Molecules

Discovery Oncology is seeking a visionary and driven people leader to discover and advance the next generation of small molecule oncology therapeutics. This role leads a Boston-based team focused on small molecules and collaborates across chemistry, clinical, translational, and business development functions to execute a portfolio of medicines.

• Be a creative and forward‑thinking leader to design and execute the future of the company’s oncology therapeutics, particularly small molecules.
• Be a thought leader for employing small molecules to create effective, tolerable, combinable medicines that are first‑in‑class and best‑in‑class.
• Leverage deep understanding of cancer biology and the internal and external oncology landscape to drive decisions on new therapeutics.
• Deliver on key pipeline milestones, such as preclinical candidates and IND filings for first‑in‑human studies.
• Be an experienced program lead and mentor others to become strong program leaders.
• Contribute expertise and vision to business‑development evaluations of molecules or platforms of interest.
• As a member of the Discovery Oncology Leadership team, meaningfully contribute to strategy development and execution and the growth and development of staff.
• Foster a high‑performance culture of collaboration, engagement, self‑accountability, and inclusion.

• Ph.D. in Biology, Immunology, Biochemistry, Pharmacology, Toxicology, Bioengineering, Biotechnology, Oncology, Biophysics, Biologics, or a related STEM field with 8+ years of post‑degree experience in industry (or MS with 10+ years of experience).
• Extensive background in cancer biology and deep knowledge of intrinsic pathways and key cancer drivers.
• Evidence of innovative approaches to small‑molecule design, particularly induced proximity.
• Proven track record of advancing well‑designed investigative new small‑molecule drugs into the clinic with a focus on patient experience and successful clinical execution.
• Clear experience in late‑stage program leadership partnering with regulatory, translational sciences, and clinical development to engage with agencies and advance investigational drugs.
• Experience writing IND modules.
• Experience managing a group of senior and junior scientists with a record of achievements, including project leadership and strategic contributions.
• Ability to build strong relationships within highly collaborative, multidisciplinary teams.
• Excellent attention to detail and strong oral and written communication skills.
• Highly self‑motivated and capable of prioritizing deliverables among multiple projects.

• Large breadth of small‑molecule experience, including novel approaches.
• Experience with modalities beyond small molecules, especially small‑molecule payloads.

• Drug Development, Drug Discovery Research, IND Amendments, IND Submission, Investigational New Drug (IND), Mentorship, Molecular Biology, Oncology, Oncology Drug Development, People Leadership, Program Management, Project Leadership, Small Molecules, Target Validation.

The salary range for this role is $ – $. The successful candidate will be eligible for an annual bonus and, if applicable, long‑term incentive. Benefits include medical, dental, vision, other insurance, retirement (401(k)), paid holidays, vacation, and compassionate and sick days.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.