Senior Director, Discovery Oncology, T-Cell Engagers

Job Description

Discovery Oncology is seeking a visionary and strategic leader to shape and drive the discovery and advancement of the next generation of our company's oncology therapeutics. Come join an incredible team steeped in a history of scientific excellence and successful drug discovery.

The successful candidate will lead a team at our company’s site in Boston, delivering on the oncology pipeline. They will serve as the strategic leader for oncology protein‑based therapeutics in Boston, including T cell engagers. The role involves developing and executing a comprehensive pipeline strategy, partnering across the organization to expand our portfolio, and working closely with clinical, translational, and business development colleagues to move an effective pipeline of compelling medicines from discovery through late‑stage development.

The candidate must have a strong record of scientific excellence, thoughtful strategic planning, and inspiring people leadership.

• Develop and execute a forward‑thinking pipeline strategy, shaping the future of our oncology therapeutics with a focus on T cell engagers and other protein‑based modalities.
• Leverage deep understanding of cancer biology and the current oncology landscape to evaluate opportunities for new therapeutics.
• Provide strategic oversight for programs as they transition from early discovery into and through late‑stage clinical development, ensuring continuity and alignment with the overall asset strategy.
• Drive key milestones for pipeline advancement, from preclinical candidate selection through to IND‑enabling studies and support for early clinical development.
• Lead business development evaluations from a scientific perspective, identifying and championing external assets and platforms that align with our strategic vision.
• As a member of the Discovery Oncology Leadership team, meaningfully contribute to the development and execution of strategy and the growth and development of staff.
• Foster a high‑performance culture of collaboration, engagement, self‑accountability, and inclusion. Establish strong relationships within highly collaborative, multidisciplinary teams to effectively drive drug discovery initiatives.

• Ph.D. in Biology, Immunology, Biochemistry, Pharmacology, Toxicology, Bioengineering, Biotechnology, Oncology, Biophysics, Biologics or a related STEM field with 10+ years of post‑degree experience in industry or equivalent.
• Extensive background in immuno‑oncology with a proven ability to translate deep scientific insights into drug development strategies from discovery through late‑stage development.
• Proven track record of successfully advancing multiple drug candidates into the clinic, including direct, hands‑on experience with IND filings.
• Experience managing a group of senior and junior scientists with a track record of achievements, including project leadership and strategic contributions.
• Excellent attention to detail and strong communication (oral and written) skills.
• Highly self‑motivated and capable of prioritizing deliverables among multiple projects.

• Deep T cell biology background with extensive biotech/pharmaceutical experience.
• Experience with modalities beyond T cell engagers, particularly including antibody–drug conjugates.

Assay Development, Biochemistry, Biologics, Cancer Biology, Cancer Cell Biology, Cell Biology, Drug Discovery Research, Immunology, Immunotherapy, Innovation, Mentorship, Molecular Biology, Multidisciplinary Collaboration, Oncology, People Leadership, Strategic Management, Strategic Planning, T Cell Biology, T Cell Immunology, Tumor Biology.

$ – $. This range reflects the expected compensation for the position. Salary within the range is determined by relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and organizational needs.

We offer a comprehensive benefits package that includes medical, dental, vision, and other health insurance options for employees and families; retirement benefits, including a 401(k); paid holidays, vacation, compassionate leave, and sick days. Additional details are available at

Employee Status:
Regular
Relocation:
Domestic
VISA Sponsorship:
Yes
Travel Requirements: 10%

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. We comply with all affirmative action requirements for protected veterans and individuals with disabilities.