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Senior Software Engineer

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Sophia Genetics SA
Full Time position
Listed on 2026-02-16
Job specializations:
  • Software Development
    Software Engineer, Cloud Engineer - Software, Senior Developer
Salary/Wage Range or Industry Benchmark: 125000 - 150000 USD Yearly USD 125000.00 150000.00 YEAR
Job Description & How to Apply Below

Overview

Are you an experienced Software Engineer with a passion for building and improving scalable, high-performance systems? Are you looking for a team that embraces fresh ideas, encourages an agile approach, and ensures your voice is heard and your contributions truly make an impact?

If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Software Engineering team as our new Senior Software Engineer
, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.

This is a hybrid opportunity, requiring 3 days onsite our corporate office in Rolle, CH.
Please ensure that all CV/Resumes are submitted in English as we are an international company that uses English as our language of business.

Our Mission

We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.

Your Mission

As our Senior Software Engineer
, you will be responsible for developing, optimizing, and continuously improving core systems, while contributing to technical initiatives and ensuring solutions meet both business and technical requirements. The components you ll work on and own are essential to SOPHiA GENETICS’ DDM operations and enable integration with external hospital systems, unlocking the potential for processing of medical data into insights for oncologists at high volumes.

These components span the technology stack and enable AI algorithms processing medical data to have a real-world impact via a robust and scalable architecture. Your expertise will ensure these components not only scale effectively but also remain efficient in terms of performance and cost, while maintaining overall system health. By implementing cutting edge clinical diagnostic workflows through system integrations at prominent healthcare institutions, you will have direct impact on the acceleration of progress of healthcare.

The

value you bring

System Development & Improvement/ Maintenance:

  • Design, develop, and continuously improve robust services and workflows that are scalable and efficient
  • Implement enhancements based on evolving business and technical requirements.
  • Ensure components are seamlessly integrated and perform reliably under workloads.
  • Optimize system performance, resource utilization, and task execution times.

New Feature Development:

  • Interact with internal and external stakeholders to understand and refine requirements
  • Develop and implement new features and components to support changing business needs.
  • Set up smart fully automated tests covering all use cases and requirements for long term maintainability

Deployment & Infrastructure Automation:

  • Optimize deployment workflows, automate pipelines, and enhance infrastructure management for efficient and reliable application deployment.
  • Contribute to improvements in system stability, minimizing downtime and ensuring seamless rollouts.

Monitoring & Observability:

  • Implement and maintain monitoring systems to track performance and identify bottlenecks.
  • Use observability tools like Grafana and Loki to improve system reliability and provide insights into operational health.
Requirements
  • Proficiency in Java for backend service engineering
  • Extensive experience working on large-scale systems with microservice architecture
  • Experience with React.js or other modern web UI development framework
  • Experience in optimization of system performance, managing resources effectively and improving execution time - especially when dealing with very large data volumes
  • Proficiency with databases like MySQL, Maria

    DB, and DuckDB, including design and query optimization
  • Familiarity with Linux environments and Git Lab for version control and CI/CD pipelines.
  • Experience with scalable architecture, particularly in cloud environments and containerized infrastructure
  • Familiarity with monitoring and observability tools like Grafana and Loki
  • Experience in Micronaut for developing microservices and backend solutions is a strong plus.
  • Experience with HL7 / FHIR protocols for healthcare interoperability is a strong plus
  • Work experience in a direct customer facing role is a strong plus
  • Knowledge of Kafka is a plus
  • Experience in genomics is beneficial
Benefits

You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth.

Business recognition and accolades include:

  • World s most innovative companies (Top 10)
  • World s smartest companies (Top 50)
  • 100 Best Places to Work in Boston
  • Top 10 European Tech Startup
  • Top 10 European biotechs startup to watch
  • Top 25 East-Coast Biotech to watch

Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview:

  • Sickness and…
Position Requirements
10+ Years work experience
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