AI​/ML Software Engr, Navigation

Staff AI/ML Software Engineer

Fueled by innovation at the intersection of biology and technology, we're developing the next generation of smarter, less invasive, more personalized treatments.

Are you passionate about improving and expanding the possibilities of Orthopaedics? Ready to join a team that's reimagining how we heal? Our Orthopaedics teams help keep more than 6 million people moving each year while delivering clinical and economic value to surgeons and healthcare systems. Our teams build solutions for joint reconstruction; trauma and craniomaxillofacial; sports, extremities, and elective foot and ankle;

spine; and robotics and digital surgery.

Your unique talents will help patients on their journey to wellness.

We are hiring for Staff AI/ML Software Engineer in a hybrid role to be based out of Warsaw, IN or Boston, MA.

Purpose:

As a Staff AI/ML Software Engineer in the Navigation R&D team, you will architect, plan and lead the AI/ML development and integration for next‑generation surgical navigation and planning systems. You'll collaborate closely with a cross-functional team of software, systems, hardware, firmware, quality, and regulatory partners to deliver safe, reliable, and scalable software that directly impacts patient outcomes.

Job Responsibilities:

• Be a key contributor in the evolution of DePuy Synthes' AI/ML platform for flexible machine learning model training, fine-tuning, transformation and evaluation use cases across various surgical navigation initiatives.
• Participate in product planning sessions to accurately define development timelines.
• Build production ready, on‑device and cloud-based, AI/ML systems with real clinical impacts to our customers.
• Mentor junior AI/ML software engineers.
• Drive model improvements using the latest techniques and approaches for evaluation and tuning.
• Contribute to regulatory documentation, traceability, and V&V aligned with IEC 62304, ISO 14971, and related guidance; support submissions (e.g., FDA 510(k)) as needed.
• Collaborate in Agile/Scrum workflows, mentor junior engineers, and lead design/code reviews to sustain long‑term maintainability.

Required Qualifications and

Experience:

• BS/MS in Machine Learning, Artificial Intelligence, Computer Science, Computer Engineering, or a related field
• 8+ years of experience in machine learning engineering (or equivalent)
• Highly proficient in Python
• Strong AI/ML fundamentals – Strong grounding in supervised and unsupervised learning, model section, cross-validation, and evaluation metrics
• Hands-on experience developing machine learning models using various input data types (static images, point clouds, numerical data, textual data, etc.)
• Demonstratable experience and deep knowledge of ML frameworks such as Tensorflow, Keras, Pytorch, scikit-learn, etc.
• Demonstratable expertise in ML model training/optimization, local/cloud (AWS Sagemaker, Azure Studio)
• Experience developing AI systems in regulated environments (e.g., SaMD), such as surgical, medical imaging, or healthcare-related ML/AI applications, with attention to traceability, validation, and auditability.
• Excellent ability to author technical documentation for AI/ML training and implementations.
• Proficiency across the full SDLC in a regulated environment: requirements, design, implementation, testing, traceability, release, and maintenance.
• Excellent communication, collaboration, and influence skills; ability to lead architecture and design reviews.

Preferred Qualifications

• Demonstrated experience in applying multiple types of AI technologies to products beyond traditional Machine Learning (Agentic AI, Generative AI, LLMs) (Big plus)
• Experience with on-device and cloud-based AI/ML implementations.
• Experience with AI-driven development and testing.
• Demonstratable experience with one or more object-oriented programming languages.
• Experience with requirements, design documentation in tools like Polarion, JAMA, etc.

Johnson & Johnson announced plans to separate our Orthopaedics business to establish a standalone Orthopaedics company, operating as DePuy Synthes. The process of the planned separation is anticipated to be completed within 18 to 24 months, subject to legal…