Clinical Laboratory Scientist II

Location

Onsite, Boulder, Colorado, United States

Foresight Diagnostics is a molecular diagnostics company advancing non-invasive cancer detection through highly sensitive, cell-free DNA–based liquid biopsy technologies. Our proprietary methods, originally developed at Stanford University, are designed to enable earlier detection of smaller tumors and support more personalized, effective cancer treatment strategies.

We operate at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), translating rigorous scientific innovation into clinically meaningful solutions. As our organization has grown, we have built robust laboratory operations, cross-functional collaboration, and scalable processes to support clinical development and long-term commercial readiness.

Foresight Diagnostics offers a collaborative, high-accountability work environment where quality, precision, and continuous improvement are core to how we operate. Team members have the opportunity to contribute to impactful programs, work alongside experienced scientific and operational leaders, and grow professionally within a well-resourced and mission-focused organization. Foresight Diagnostics is headquartered in Boulder, Colorado.

The Clinical Laboratory Scientist II will be responsible for performing a variety of laboratory procedures involved in end-to-end processing of biological samples to enable successful downstream next-generation sequencing (NGS). Processing will include accessioning and both manual and automated extraction, library preparation, hybrid capture, sequencing and QC steps. Under the guidance of the Director of Clinical Laboratory Operations and the Laboratory Director, you will work collaboratively within the clinical laboratory leveraging your technical knowledge, skills and abilities to ensure efficient and quality results are provided to our clients and patients while also informing/participating in process improvements.

This position will report to the Lab Manager.

• Bachelor’s or Master’s degree in chemical, physical, biological, or clinical laboratory science or medical technology from an accredited institution.
  • Education received at a college or university located outside of the United States or United States Territories requires a credentials equivalency evaluation by an approved agency.
• Hold a current and active American Society of Clinical Pathology (ASCP) board certification.
• Hold current and valid Clinical Laboratory Scientist licensure (Generalist or CGMBS).
• Demonstrate a working knowledge of the general biological principles that govern DNA biology.
• Possess a strong foundational understanding of common molecular biology techniques, such as PCR/qPCR, DNA ligation, and DNA extraction.
• Work‑level knowledge or ability to learn use of common molecular biology instruments;
  Agilent Tape station/capillary electrophoresis, Qubit, plate readers, thermocyclers and other common laboratory instruments.
• Previous experience handling human biological materials is required.
• Working knowledge of how to safely operate in a BSL‑2 environment is required.
• Previous experience handling, processing, and extracting DNA from biological specimens is required.

• Perform routine and complex diagnostic laboratory testing on patient samples for clinical, biopharma, and academic partnerships.
• Provide technical guidance and oversight to non‑licensed personnel for pre‑analytical, analytical and post‑analytical activities.
• Interpret data and results of all analyses according to set procedures and guidelines.
• Support day‑to‑day operations by assisting with data entry, receiving samples and consumables, reagent preparation, sample preparation, temperature recording, laboratory maintenance and documentation.
• Identify and resolve problems that may adversely affect test performance or reporting of test results following the escalation path to clinical leadership as needed.
• Assist with research, translational research, regulated products through the execution of partnership studies and internal/external validation studies.
• Participate as a…