Clinical Laboratory Scientist II

About our Company:

Foresight Diagnostics is a molecular diagnostics company pioneering non-invasive cancer detection through highly sensitive, cell-free DNA-based liquid biopsy technologies. Our proprietary methods - originally developed at Stanford University - are designed to detect smaller tumors earlier and enable more personalized treatment strategies for patients with cancer.

We sit at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), and we translate rigorous science into clinically meaningful solutions. Following our acquisition by Natera, we now combine the agility of a mission-driven startup with the scale and resources of a global leader in cell-free DNA testing. It’s an exciting moment to join us.

Headquartered in Boulder, Colorado, our team operates in a high accountability, collaborative environment where quality and continuous improvement aren’t just values - they’re how we work every day.

The Clinical Laboratory Scientist II will be responsible for performing a variety of laboratory procedures involved in end-to-end processing of biological samples to enable successful downstream next-generation sequencing (NGS). Processing will include accessioning and both manual and automated extraction, library preparation, hybrid capture, sequencing and QC steps. Under the guidance of the Director of Clinical Laboratory Operations and the Laboratory Director, you will work collaboratively within the clinical laboratory leveraging your technical knowledge, skills and abilities to ensure efficient and quality results are provided to our clients and patients while also informing/participating in process improvements.

This position will report to the Lab Manager.

Bachelor’s or Master's degree in chemical, physical, biological, or clinical laboratory science or medical technology from an accredited institution

Education received at a college or university located outside of the United States or United States Territories requires a credentials equivalency evaluation by an approved agency

Hold a current and active American Society of Clinical Pathology (ASCP) board certification

Hold current and valid Clinical Laboratory Scientist licensure (Generalist or CGMBS)

Demonstrate a working knowledge of the general biological principles that govern DNA biology

Possess a strong foundational understanding of common molecular biology techniques, such as PCR/qPCR, DNA ligation, and DNA extraction

Working level knowledge or ability to learn use of common molecular biology instruments;
Agilent Tape station/capillary electrophoresis, Qubit, plate readers, thermocyclers and other common laboratory instruments

Previous experience handling human biological materials is required

Working knowledge of how to safely operate in a BSL-2 environment is required

Previous experience handling, processing, and extracting DNA from biological specimens is required

Perform routine and complex diagnostic laboratory testing on patient samples for clinical, biopharma, and academic partnerships.

Provide technical guidance and oversight to non-licensed personnel for pre-analytical, analytical and post-analytical activities.

Interpret data and results of all analyses according to set procedures and guidelines.

Support day to day operations by assisting with data entry, receiving samples and consumables, reagent preparation, sample preparation, temperature recording, laboratory maintenance and documentation.

Identify and resolve problems that may adversely affect test performance or reporting of test results following the escalation path to clinical leadership as needed.

Assist with research, translational research, regulated products through the execution of partnership studies and internal/external validation studies.

Participate as a