IT Systems Engineer

Experience: Associate required, Bachelors preferred, + 5 years relevant experience

Watchmaker Genomics is a global life science company based in Boulder, Colorado with an R&D and Production facility in Cape Town, South Africa. Our team is passionate about innovation and values collaboration, creativity, and scientific rigor.

We believe that the intersection of biology, engineering, and computer science presents exciting opportunities for developing novel technologies that promote research and improve human health. Watchmaker Genomics specializes in the design, development, and production of DNA- and RNA-modifying enzymes that enable high-growth applications in genomics, molecular diagnostics, and personalized medicine.

Watchmaker Genomics is inviting applications for the full-time position of IT Systems Engineer, an onsite role in our Boulder, Colorado office. This position reports to the Director IT, Boulder site for day-to-day execution and service delivery. The position will implement and maintain IT infrastructure and cloud services, change management, problem identification and resolution, and configuration management activities. Additionally, this position is expected to assist in the creation of new processes, work instructions, infrastructure documentation and knowledge base articles.

The successful candidate will thrive in a dynamic, fast-paced working environment and contribute directly to our company culture and success. This position will offer unique challenges, learning and growth including the opportunity to build and supervise a global service desk team.

• System Design and Architecture: Implement complex IT infrastructure, including servers, storage, networks, and cloud services, in line with Watchmaker's global architecture standards.
• Identity and Access Management (Microsoft Entra): Administer identity, authentication and access management in Microsoft Entra, including conditional access, multi-factor authentication, and joiner/mover/leaver processes.
• Cloud Infrastructure: Build, administer, and maintain infrastructure and cloud services in line with global standards.
• Endpoint Management: Manage Windows endpoints and macOS endpoints, including enrollment, compliance, configuration baselines, and application deployment.
• Security and Cyber Security Protection: Operate security systems across endpoints and cloud workloads; monitor, triage, and respond to security alerts; execute patch and vulnerability management.
• Network Infrastructure: Configure, maintain, and troubleshoot the site network infrastructure, including switching, wireless, firewalls, and VPNs. Advanced network knowledge and hands-on network infrastructure configuration are essential for this role.
• System Administration and Maintenance: Execute or oversee the installation, configuration, and maintenance of servers, virtual environments, and enterprise applications.
• Performance Monitoring and Optimization: Monitor system performance, troubleshoot issues, and optimize infrastructure for stability, security, and efficiency.
• Automation and Scripting: Develop and use automation tools/scripts to streamline operations and system management.
• Computer Systems Validation: Perform required Computer Systems Validation actions.
• Documentation and Operational Discipline: Maintain accurate and current infrastructure documentation, work instructions and knowledge base articles; execute all changes through formal change management.
• Risk Management and Escalation: Proactively identify, communicate, and elevate risks, incidents and capacity constraints.

• Disaster Recovery Planning: Design and implement disaster recovery (DR) plans, ensuring critical systems and data can be restored in case of failure or outage.
• Backup Management: Oversee regular backups of data, systems, and configurations, ensuring that backups are complete, secure, and recoverable.
• System Redundancy: Implement and maintain redundancy for key systems (e.g., servers, storage, network components).
• Disaster Recovery Testing: Conduct regular DR testing and simulations to validate the effectiveness of recovery plans, ensuring systems can be restored according to recovery time objectives and recovery point objectives.
• Incident Response: Lead response efforts during major system outages or disasters, coordinating recovery activities, and communicating status updates to stakeholders.
• Documentation and Updates: Maintain detailed documentation of continuity and recovery procedures.

• System Diagnosis: Identify, analyze, and resolve issues related to servers, networks, storage, and applications.
• Root Cause Analysis: Investigate recurring problems to determine the underlying causes and implement long-term solutions.
• Performance Issues: Troubleshoot slow or underperforming systems by analyzing resource usage (CPU, memory, disk) and resolving bottlenecks.
• Network and Connectivity Issues: Diagnose and resolve network…