Postdoctoral Associate

Postdoctoral Associate Position

The Ledo Laboratory, at the Institute for Behavioral Genetics, University of Colorado Boulder (CU Boulder) invites applications for a Postdoctoral Associate position, to investigate how neuroimmune pathways regulate the formation, elimination, and plasticity of synapses during learning and memory in health and neurodegeneration. A major goal of the laboratory is to elucidate the cellular and molecular mechanisms underlying synapse remodeling in health and disease, with an emphasis on the roles of microglia, immune molecules, and neuron-immune interactions in shaping neural circuit function.

By leveraging transformative technologies at the convergence of systems genetics, systems neuroscience, and human cellular models, the Ledo Lab seeks to address major questions related to memory processes in health, Alzheimer's disease, and neurodevelopmental risk states. Current projects use mouse models of Alzheimer's disease and maternal immune activation, immunometabolism as well as human iPSC-derived microglia and neuron-microglia co-culture systems, to define how immune pathways influence synaptic function, neuronal activity, and cognitive outcomes.

CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

The Institute for Behavioral Genetics (IBG) is an organized research unit of the University of Colorado Graduate School dedicated to conducting and facilitating research on the genetic and environmental bases of individual differences in behavior. Within IBG, the Ledo Lab uses a combination of cutting-edge technologies, including transcriptomics, iPSC-based disease modeling, immunofluorescence, confocal microscopy, flow cytometry, synaptic and cellular assays, and in vivo neuronal activity measurements.

• Design and execute experimental approaches to study neuro-immune interactions in neurodegeneration and neurodevelopment
• Stay up to date with relevant scientific literature and contribute to lab and department discussions
• Assist in training and supervising graduate students, technicians, and junior lab members
• Maintain an organized, comprehensive lab notebook and data management process
• Prepare and contribute to manuscript publications
• Present research at local, national, and international conferences and contribute to manuscript and grant proposal writing

The ideal candidate will bring expertise in neuroimmunology, Alzheimer's disease models, maternal immune activation, iPSC-derived cellular systems, confocal microscopy, flow cytometry, or related approaches. Experience programming, bioinformatics, or computational analysis is a plus.

• Salary $71,000 per year
• Relocation assistance is available depending on department guidelines
• This position provides an exceptional opportunity to advance your career in neuroscience, working with state-of-the-art tools in a dynamic and collaborative environment.
• CU Boulder offers a competitive benefits package to support your professional and personal wellbeing

At the University of Colorado Boulder, we are committed to supporting the holistic health and well-being of our employees. Our comprehensive benefits package includes medical, dental, and retirement plans; generous paid time off; tuition assistance for you and your dependents; and an ECO Pass for local transit. As one of Boulder County's largest employers, CU Boulder offers an inspiring academic community and access to world-class outdoor recreation.

Explore additional perks and programs through the CU Advantage program.

Be ambitious. Be groundbreaking. Be Boulder.

• Ph.D. in Neuroscience, Molecular Biology, Immunology, Neurology or a related field
• Hands-on experience with transgenic mouse models, including intraperitoneal and tail vein injections and rodent general surgeries
• Experience with histological procedures, immunofluorescence, confocal microscopy, or flow cytometry
• Excellent oral and written communication skills in English
• A strong record of publication in peer-reviewed journals
• Ability to work independently in experimental design and project execution
• Enthusiasm for working in a highly collaborative, team-oriented environment

To apply, please submit the following materials:
Resume or CV Cover Letter addressed to the Search Committee briefly describing your qualifications, professional goals, and specific interest in the position One (1) Letter of Recommendation (not confidential)

If you are selected as the finalist, your degree will be verified by the CU Boulder Campus Human Resources department using an approved online vendor. If your degree was obtained outside the United States, please submit a translated version as an optional attachment. This position…