Lead Research Technician

## Lead Research Technician Apply remote type:
On-site locations:
Boulder, CO (E) time type:
Full time posted on:
Posted Yesterday job requisition :
JR101626
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* Job Summary:

** The lead research technician assists Gastrointestinal and Rheumatology team personnel in coordinating efforts on the day-to-day operations of active studies. S/he assists Study Directors and Study Coordinators in accurately and efficiently conducting animal studies and supervises the in-life study execution, clinical observations, and treatments to ensure compliance with policies and procedures. S/he also provides leadership, training, and technical oversight to more junior technicians.
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* Primary Responsibilities:

*** Directly works with the Gastrointestinal and Rheumatology group to conduct required study activities.
* Assists in disease induction procedures.
* Assist with the preparation and execution of necropsies, tissue collection (terminal and interim) and surgeries for gastrointestinal and rheumatology studies.
* Review facility schedules, dose formulation calculations, cage cards, spreadsheets, and study protocols for consistency and accuracy before the first dose event.
* Independently perform tissue collections, dosing, and necropsies after training with PI.
* Read and understand and assist with development of IACUC protocols, SOPs, and all study protocols, demonstrating familiarity with critical time points.
* Perform critical data collections for gastrointestinal and rheumatology studies, including weighing, clinical observations, health assessments, post operative monitoring, and disease progression scoring.
* Administer doses of compounds to rats and mice via common dosing routes, including but not limited to oral, intravenous, intrarectal, subcutaneous, and intraperitoneal injection.
* Perform blood collections from rats and mice via tail vein, jugular, submandibular, retro-orbital, and terminal blood draws and process these samples via centrifugation for plasma and/or serum.
* Review live phase data on all active studies for consistency and accuracy.
* Assist in formulating experimental compounds for administration.
* Use of general laboratory equipment, including but not limited to balances, syringes and needles, blood collection tubes, centrifuges, pipettes, formalin collection jars, liquid nitrogen,
-80°C freezers, incubators, fluid/syringe pumps, chemical and clean hoods, PPE (lab coat, gloves, face mask or respirator, shoe covers, hair nets, eye protection), quarantine/isolation rooms, autoclaves, and necropsy hand tools.
** Secondary Responsibilities:
*** Assist Study Directors and Study Coordinators to ensure study protocol, schedules, formulations, and sample collections are correct and properly communicated to the research team.
* Assists Study Coordinators with the creation or verification of cage cards, sample collection prep labels, and data files.
* Maintain study-related forms (
* e.g.
* data sheets, health assessments, found dead forms, and moribund forms)
* Keep laboratory clean and maintain inventory of all team supplies (
* e.g.
* media, plates, reagents, surgical tools, etc.) and study-specific test articles.
* Support and participate in other duties and company initiatives as directed.
* Utilize various software applications sustained by a Windows platform. (Excel, Word, PowerPoint, etc.)
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* Education & Experience:

*** M.S./B.S./B.A. in science (biology or equivalent; immunology preferred) with 1-3 years of direct animal behavioral work experience, or Associate degree with 4 years direct laboratory animal work experience, or 6 years of direct laboratory animal work experience without a college science degree, or equivalent combination of related education and required work experience will be considered with management approval.
* AAALAS Certification or commitment to attaining certification within 18 months of start date.
* Preferred animal laboratory research experience with mice and rats, including dosing, in-life sample collections, and necropsy collections.
** Skills & Abilities:
*** Demonstrates a working knowledge and awareness of general laboratory procedures.
* Demonstrates an ability to follow detailed…