Research Project Manager

Cogent Biosciences is a publicly traded biotechnology company focused on developing novel precision therapies to treat a broad range of patients with unmet medical needs. Cogent’s lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V. KIT D816V is responsible for driving a rare and serious condition called Systemic Mastocytosis, and exon 17 mutations are also found in patients with gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling.

Bezuclastinib has exhibited promising initial data across all three trials: APEX in AdvSM, SUMMIT in NonAdvSM and PEAK in GIST, including an encouraging safety profile across 600+ patients in single‑agent and combination dosing.

The Research Project Manager drives planning, execution, and communication within and across discovery research programs. This role partners closely with cross‑functional scientific stakeholders to ensure clear priorities, integrated plans, and on‑time delivery of key program milestones. Works independently, can manage interactions with and between internal teams and external partners, and brings strong program operations capability in a fast‑paced biotech environment.

• Support integrated research program plans by building and maintaining timelines, dependencies, and critical paths across discovery and preclinical activities; proactively communicate progress, risks, and mitigation plans to stakeholders.
• Organize focused sub‑project and ad hoc meetings, agendas, decision logs, action items, and follow‑ups; ensure clarity on deliverables and accountability across functions.
• Coordinate study execution and logistics to support program needs, including scheduling work, coordinating shipments, tracking key documents, and ensuring timely handoffs between internal teams and external partners.
• Support outsourcing and external partner oversight (e.g., CRO/vendor coordination) by tracking deliverables, timelines, and data outputs; facilitate alignment across internal teams and external providers. Ensures appropriate agreements are in place for interactions with external partners or scientific collaborators.
• Enable inspection‑ready documentation habits by supporting document organization, version control, and readiness for internal reviews; assist cross‑functional teams with contributions to program documentation as needed.
• Coordinate internal documentation/report writing and preparation of regulatory filings for nonclinical team, including establishment of appropriate works flows, process controls, timelines and communication.
• Continuously improves project management tools and processes, including creating fit‑for‑purpose trackers and dashboards that keep stakeholders informed with minimal friction.

• BA/BS in science related discipline with 5+ years of related experience.
• Demonstrated experience in research project/program management within pharma/biotech settings, including work supporting drug discovery / life sciences programs.
• Experience partnering with teams working in oncology / clinical development environments and coordinating with external providers (e.g., nonclinical CROs).
• Strong ability to work independently, manage multiple concurrent priorities, and bring structure to ambiguous, fast‑moving scientific environments.
• Solid grammar, spelling, and math skills required to appropriately assist with report generation.
• Proven strength in stakeholder communication—able to express oneself clearly and concisely and align diverse teams around timelines, decisions, and next steps.
• Basic to advanced understanding of contracts needed to support discovery functions.
• High attention to detail with strong organizational skills (meetings, action tracking, documentation discipline).
• Comfort building and maintaining practical tools for project execution (plans, trackers, cost/budget rollups, decision logs).
• Onsite position in Boulder, CO

$95, USD

Exact compensation will vary based on skills, experience, and location.

Waltham, MA:
Our headquarters is located…