Senior Manager Clinical Operations

Johnson & Johnson is seeking a driven Senior Clinical Research Manager to join our growing Clinical Operations team in The Netherlands (Breda) and Belgium (Beerse). In this role, you will manage a team of Local Trial Managers, Site Managers, and Clinical Trial Assistants, focusing on trial delivery in oncology, site engagement, staff development, training/onboarding, and resource management. The Senior Clinical Research Manager is responsible for the successful execution of trials from country feasibility through study close-out while maintaining oversight of quality & performance indicators, timelines, and compliance with SOPs, HCC, and local regulatory requirements.

• People management: Provide line management to your team including goal setting, performance evaluation, and talent development; build, hire, and train a fully effective team; conduct accompanied site visits; evaluate and forecast resource needs and manage your team's workload.
• Trial delivery & oversight: Accountable for robust feasibility processes and oversight of site selection; responsible for start-up, execution, and monitoring of trials in assigned therapeutic area(s); empower your team to deliver and think out of the box; ensure inspection readiness at all times, adherence to ICH‑GCP, local legislation and relevant SOPs; support your team in site engagement, issue resolution, and stakeholder management;
  
  support audits, inspections and timely CAPA resolution; build and shape internal and external network in assigned therapeutic area.
• Continuous improvement & organizational change: Lead implementation of innovation and inspire change in the local organization; cultivate an environment that encourages shared learning, out of the box thinking and a "Yes we can!" mentality; contribute to the development of new processes or improvement initiatives; keep close oversight of metrics and drive follow‑up actions proactively.
• Co‑develop country strategy and drive tactics to full implementation.
• Help shape the Dutch Clinical Trial Landscape.
• Participate in special (global) initiatives as assigned. May assume additional responsibilities or special initiatives such as "Champion" or "Subject Matter Expert".

• BA/BS degree in Life Sciences or related scientific field (or 8‑10 years equivalent experience) with a minimum of 8 years of Clinical Research experience in pharmaceutical industry, CRO or investigational site. Other relevant working experiences and skills may be considered by the hiring manager.
• At least 2 years of line management experience desirable.
• Proven leadership & communication skills – ability to champion team productivity and cohesiveness.
• Solid decision‑making and effective issue resolution skills; ability to generate & implement contingency plans for productivity & quality issues.
• Strong interpersonal & influencing skills; willingness to engage with internal and external stakeholders (key sites, trade association, authorities and ethics committees).
• Flexible mindset and ability to work in a constantly evolving environment with the ability to collaborate and handle multiple priorities in a matrix environment.
• Strong proven understanding of GCP, local laws, and regulations.
• Proficient in English and Dutch; for candidates based in Belgium, proficiency in French is also required.

• Budgeting
• Clinical Trial Designs
• Clinical Trials
• Compliance Management
• Contract Management
• Developing Others
• Execution Focus
• Fact-Based Decision Making
• Inclusive Leadership
• Laboratory Operations
• Leadership
• Process Improvements
• Productivity Planning
• Project Integration Management
• Research and Development
• Research Ethics
• Resource Planning
• Team Management

• Budgeting
• Clinical Trial Designs
• Clinical Trials
• Compliance Management
• Contract Management
• Developing Others
• Execution Focus
• Fact-Based Decision Making
• Inclusive Leadership
• Laboratory Operations
• Leadership
• Process Improvements
• Productivity Planning
• Project Integration Management
• Research and Development
• Research Ethics
• Resource Planning
• Team Management