AI Engineering Senior Principal

Premise Health is Different on Purpose

Premise Health serves large organizations and their people with exceptional healthcare. The result? Better experiences, better health, and better value, all while helping organizations lower their healthcare costs.

Premise's mission is to help people get, stay, and be well. Come join us and see for yourself why amazing health starts with amazing healthcare. For more information, visit

As the AI Engineering Senior Principal, you will serve as the strategic leader and architect for Premise Health's AI engineering initiatives, responsible for defining and implementing enterprise-wide AI architecture, strategy, and best practices. This role combines deep technical expertise in artificial intelligence, information security, cloud architecture, and enterprise systems with strong leadership capabilities to build and guide the organization's AI transformation.

The ideal candidate will have extensive experience in healthcare technology, information security architecture, AI/ML solutions, cloud-native application development, and agile methodologies. This position requires a visionary leader who can bridge the gap between business strategy and technical execution while ensuring security, compliance, scalability, and operational excellence across all AI initiatives.

This is a Full Time, remote AI Engineering Senior Principal role.

What You'll Do

* Define and lead the enterprise AI architecture strategy for Premise Health, establishing architectural principles, standards, patterns, and best practices for AI/ML solutions across the organization.

* Design and architect secure, scalable AI solutions leveraging Large Language Models (LLMs), Retrieval-Augmented Generation (RAG), AI agents, and other advanced AI technologies while ensuring alignment with business objectives.

* Establish and enforce information security architecture for all AI systems, including Identity and Access Management (IAM), computer-to-computer authentication mechanisms, API security, data protection, and compliance with healthcare regulations (HIPAA, HITECH).

* Lead the creation of reference architectures for AI-powered applications that serve as reusable templates and accelerate development across multiple teams and business units.

* Partner with business and IT leaders to make investment decisions that balance current operational demands with long-term strategic vision for AI capabilities and innovation.

* Architect cloud-native AI solutions on Azure, AWS, and other cloud platforms, establishing patterns for microservices, serverless computing, event-driven architectures, and containerization.

* Design and implement secure API gateway strategies for both public and private APIs, ensuring proper authentication, authorization, rate limiting, and monitoring across all AI services.

* Establish Dev Ops and CI/CD practices for AI/ML solutions, ensuring continuous delivery, automated testing, model versioning, and deployment pipelines for AI systems.

* Lead cross-functional collaboration efforts between data science, engineering, security, and operations teams to deliver integrated AI solutions that meet business requirements.

* Evaluate and recommend emerging AI technologies, frameworks, and platforms based on business value drivers, return on investment, and alignment with enterprise architecture standards.

* Develop and maintain technology roadmaps for AI capabilities, identifying opportunities for automation, process improvement, and innovation using artificial intelligence and machine learning.

* Architect healthcare-specific AI solutions with expertise in health data interchange standards (HL7, FHIR) and healthcare workflow automation using AI and RPA technologies.

* Establish governance frameworks for responsible AI, including ethical AI principles, bias detection and mitigation, model explainability, and compliance with regulatory requirements.

* Lead the architecture team for AI initiatives, including recruitment, development, mentoring, and performance management of architects and senior technical staff.

* Create and maintain comprehensive architectural documentation including solution architectures, technical specifications, integration patterns, security models, and decision records.

* Conduct architectural reviews and provide technical guidance to development teams working on AI-powered services, products, and platforms.

* Design multi-tenant SaaS architectures for AI applications that support multiple regions, ensure data isolation, and provide accurate cost allocation and billing.

* Establish architectural patterns for integrating AI capabilities into existing systems, including event sourcing, pub/sub messaging, claim check patterns, sidecar patterns, and gateway patterns.

* Lead proof-of-concept and pilot initiatives to validate new AI technologies and architectural approaches before enterprise-wide adoption.

* Collaborate with information security teams to ensure all AI solutions meet security requirements for…