Senior Scientist, Discovery Process Research

Discovery & Pre-Clinical/Clinical Development

Chemical Research

Scientific/Technology

Spring House, Pennsylvania, United States of America

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We are searching for the best talent for a Senior Scientist, Discovery Process Research based in Spring House, PA.

Purpose:Our Discovery Process Research team focuses on developing novel synthetic chemistry solutions that enable and accelerate the Discovery of innovative therapeutics to treat diseases with high unmet medical need. You will be responsible for conducting research towards identifying creative solutions for chemistry problems across a portfolio of projects in the discovery space, from lead identification through selection of development candidates. Our goal is to facilitate medicinal chemistry research by finding solutions to synthetic bottlenecks, enabling access to novel chemical space and translating chemistry innovations to the development of efficient routes for the synthesis of small molecules, oligonucleotides, peptides and other emerging modalities advancing into development.

You will be responsible for: Your work will require state of the art synthetic organic chemistry skills and understanding of analytical chemistry techniques. You are expected to remain conversant with the modern chemical literature and to maintain a strong laboratory presence. Residing at the interface of Discovery and Development, Discovery Process chemists thrive by collaborating across multiple Pharmaceutical R&D disciplines. Unique to this role, Senior Scientists in Discovery Process are expected to operate with a high degree of independence for scientific decision-making to contribute to the direction and execution of Discovery programs from very early in their careers.

• Minimum of a PhD in Synthetic, Organic, Medicinal Chemistry, or related field completed by Spring of 2027 is required

• Experience in methodology development, catalysis, total synthesis or similar
• Proven track record of scientific excellence supported by peer-reviewed publications
• Ability to collaborate in a highly integrated environment and to work in a strong team with diverse backgrounds.
• Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives.
• Highly motivated candidate with strong commitment to lab work.
• Excellent oral and written communication skills, fluent in English both verbal and in writing.

• Hands on knowledge of high throughput experimentation set-ups
• Experience working in non-small molecule modalities such as peptides (solid or solution phase synthesis), bioconjugates such as ADCs, or proximity inducers

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via , internal employees contact AskGS to be directed to your accommodation resource.

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