Clinical Lab Process Development Associate - Cell Factory

Clinical Lab Process Development Associate I
- Cell Factory

Location:

United States, Massachusetts, Burlington

Posted:
Mar 09, 2026

The Genomics Platform is dedicated to solving the world’s most challenging biomedical problems through continuous development and investment in cutting‑edge technology and large‑scale research projects that are both challenging and complex. In support of continually changing initiatives, the Clinical Laboratory Process Development Associate I is committed to carrying out innovative, high‑throughput lab processes and supporting the highest quality research to understand the impacts of genetic regulation on human health and disease.

In this role, you are responsible for processing samples through a high‑throughput clinical research laboratory and meeting production goals.

Responsibilities include:

• Process samples through multi‑step pipelines for cell expansion, banking, perturbations, and screens to develop cellular models of disease and biological processes of interest to researchers.
• Maintain and optimize mammalian cell culture systems for screening experiments.
• Apply functional genomics techniques, including epigenomics, single‑cell, transcriptomics, and CRISPR‑based assays in human cells and tissues.
• Follow standard operating procedures and laboratory quality‑control policies.
• Participate in continuous improvement projects and troubleshoot process issues in accordance with change‑management procedures.
• Document and communicate results of process improvement projects and quality metrics to stakeholders.
• Provide general supervision of other laboratory personnel such as Process Development Technicians and Accessioning Technicians as required.

• BS/BA degree in Biology or Chemistry.
• At least 1 year of full‑time laboratory experience in a relevant specialty after obtaining the degree.
• Solid knowledge of basic aseptic and mammalian cell culture techniques.
• Strong analytical skills, problem‑solving ability, and innovative aptitude.
• Recent experience (within the last year) with standard cell lab equipment such as pipettes, centrifuges, biosafety cabinets, microscopes, and gel electrophoresis.
• Preferred:
  Experience with high‑throughput screening and automation, genome editing tools (CRISPR targeting), molecular biology, genomics, and cellular biology assays, single‑cell sequencing methods, iPSCs, cell lines, or primary cell culture.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. The Broad Institute will not offer visa sponsorship for this opportunity.