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Principal Statistical Programmer

Job in California, St. Mary's County, Maryland, 20619, USA
Listing for: Scorpion Therapeutics
Full Time position
Listed on 2026-07-08
Job specializations:
  • IT/Tech
    Data Engineering, Data Analyst, Data Scientist, Data Security
Salary/Wage Range or Industry Benchmark: 110000 - 130000 USD Yearly USD 110000.00 130000.00 YEAR
Job Description & How to Apply Below

Position Summary

Principal Statistical Programmer / CDISC SDTM specialist providing technical oversight and quality for statistical programming of clinical trial data; leads CDISC submission topics, process improvements, and mentors junior staff.

Essential Functions
  • Lead statistical programming activities and efficient programming techniques.
  • Create/validate/maintain analysis datasets and statistical outputs (traceability, reproducibility, reproducibility).
  • Review/create statistical analysis plans and analysis dataset specifications; prepare electronic regulatory submissions.
  • Develop and validate CDISC SDTM and regulatory deliverables (Define.xml, SDTM aCRF, cSDRG).
  • Lead/support data standardization (CRF/database design, edit checks, standard programs, presentations; CDISC SDTM/ADaM; e-submissions) and communicate e-submission requirements with regulators.
  • Participate on clinical development and regulatory submission teams.
  • Solve complex statistical programming tasks; manage study electronic subdirectories.
  • Design/create/validate global programming macros.
  • Plan and budget resources; anticipate long-term resource needs.
  • Develop/revise processes; stay current on programming techniques.
  • Provide guidance/mentoring and SOP adherence; improve templates/standardization.
Education & Experience
  • BS (Stats/Biostats/CS/Math or related) + 10+ years, OR MS + 8+ years.
  • 5+ years pharma statistical programmer experience (preferred).
  • Expert in CDISC STDM and SDTM regulatory deliverables.
  • Lead statistical programmer experience on multiple concurrent projects.
Knowledge/Skills
  • Clinical research, GCP, and regulatory requirements.
  • Strong statistical programming; highly proficient in SAS; excellent English communication.
Benefits (eligible employees)
  • Medical, dental, vision; wellness programs; EAP; life/AD&D, disability; FSA; 401(k) match; 529; PTO (11 holidays for exempt/unlimited for exempt/outlined vacation for non-exempt).
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