Director - PKDM - Molecule Portfolio Strategy & Leadership

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director - PKDM - Small Molecule Portfolio Strategy & Leadership

Let's do this. Let's change the world. In this vital role you will serve as a strategic PKDM-BA leader on cross-functional teams, driving the advancement of small molecule programs from candidate discovery through clinical development and regulatory submission. You will combine deep scientific expertise with strong project leadership skills to influence portfolio strategy, support critical development decisions, and maximize the potential of small molecule therapeutic candidates.

Key Responsibilities:

• Provide strategic PKDM-BA leadership for small molecule discovery and development programs, enabling informed decision-making and successful advancement of portfolio assets.
• Drive the progression of cross-functional project teams through scientific innovation, risk assessment, and proactive problem solving.
• Lead PKDM-BA contributions to regulatory submissions, including INDs, NDAs, and interactions with global health authorities.
• Define and execute scientific strategies that support candidate selection, optimization, development, and registration of small molecule therapeutics.
• Identify, evaluate, and implement emerging technologies and approaches that enhance understanding of drug disposition and improve development outcomes.
• Partner closely with business development teams to assess external opportunities and support scientific due diligence activities.
• Build strong collaborative relationships across therapeutic areas and partner functions to advance portfolio objectives.
• Recruit, develop, mentor, and inspire scientific talent while fostering a culture of scientific excellence and innovation.
• Contribute to organizational strategy and help shape the future direction of small molecule PKDM-BA capabilities at Amgen

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Director we seek is a seasoned leader with these qualifications.

Basic Qualifications:

Doctorate degree PhD

OR

PharmD

OR MD [and relevant post-doc where applicable] and 5 years of industry experience in Pharmaceutical Sciences, Pharmacokinetics, Drug Metabolism, Pharmacology, Chemistry, or a related discipline

OR

Master's degree and 8 years of industry experience in Pharmaceutical Sciences, Pharmacokinetics, Drug Metabolism, Pharmacology, Chemistry, or a related discipline

OR

Bachelor's degree and 10 years of industry experience in Pharmaceutical Sciences, Pharmacokinetics, Drug Metabolism, Pharmacology, Chemistry, or a related discipline.

Preferred Qualifications:

• A demonstrated track record of scientific and strategic leadership across multiple small molecule discovery and development programs.
• Extensive experience supporting regulatory submissions for small molecule therapeutics, including INDs and NDAs.
• Deep expertise in drug disposition, pharmacokinetics, and translational strategies that inform candidate progression and development decisions.
• Proven success accelerating project advancement and influencing key portfolio decisions within a matrixed…