Research - Pediatrics Infectious Diseases

Scheduled Hours

40

Our research program investigates the pulmonary host immune response to bacterial infection (primarily Streptococcus pneumoniae). We have two lines of investigation, both supported by mouse models and in vitro systems. The first explores how actin cytoskeletal elements support cell motility, phagocytosis, and integrin-based mechanotransduction to NLRP3 inflammasome activation. The second analyzes a non‑canonical function of the mitochondrial enzyme Co‑enzyme Q6 in regulating the cellular balance between OXPHOS and glycolysis at homeostasis and in response to inflammation.

We have substantial unpublished, preliminary data to support multiple clinically relevant projects through either line of investigation. Although we have recently focused on macrophage biology, we have expertise and can support anyone interested in lymphocyte biology. We invest deeply in the team and prioritize the personal and professional growth of those who work with us.

This is a full‑time wet‑lab bench research position. Mouse handling is required. The role involves performing experimental work in mouse models and in vitro systems to investigate host immune responses.

The position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

• Bachelor’s degree or combination of education and/or experience may substitute for minimum education.
• No specific certification/professional license is required.
• No specific work experience is required.
• Driver’s license is not required.

• 5+ years of wet‑lab research experience in a similar biomedical background.
• Communication, Laboratory Research, Organizing, Recordkeeping, Working Independently.

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.