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Scientist, -Throughput Protein Expression and Purification

Job in Brisbane, San Mateo County, California, 94005, USA
Listing for: Scorpion Therapeutics
Full Time position
Listed on 2026-09-14
Job specializations:
  • Research/Development
    Research Scientist, Biotech Research, Biotechnology, Drug Discovery
Salary/Wage Range or Industry Benchmark: 90000 - 130000 USD Yearly USD 90000.00 130000.00 YEAR
Job Description & How to Apply Below
Position: Scientist, High-Throughput Protein Expression and Purification
Location: Brisbane

Role

Scientist specializing in high-throughput biologics production within Discovery Biotherapeutics, supporting antibody and multispecific discovery workflows.

Responsibilities
  • execute and optimize scalable mammalian protein expression, purification, normalization, and quality assessment;
  • operate and troubleshoot automation platforms;
  • develop reproducible workflows;
  • collaborate across Protein Sciences, Molecular Biology, Automation, Data Science, and Discovery Biology teams;
  • evaluate emerging technologies for throughput and quality improvements;
  • document and ensure data integrity and safety.
Requirements
  • Bachelor's degree in biochemistry, bioengineering, or related field with 5+ years, or master's with 3+ years, or Ph.D. with relevant experience;
  • hands-on expertise in mammalian expression systems (HEK
    293/CHO), protein purification, cloning, and high-throughput workflows;
  • strong problem-solving and communication skills;
  • ability to independently design experiments and manage evolving priorities.
Preferred
  • experience with laboratory automation, analytical protein quality methods (SEC, HPLC, SDS-PAGE), cell-free expression, workflow scripting (Python, R), and digital data systems (ELN, LIMS).
High-Value
  • biologics discovery, therapeutic antibodies, multispecifics;
  • workflow automation and scale-up;
  • collaboration with cross-functional teams;
  • focus on throughput, reproducibility, and continuous improvement.
Work setup

not explicitly specified; role involves laboratory execution, automation, and cross-team interactions.

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