Accountant, Financial Reporting

Company Overview

Repertoire Immune Medicines is a clinical‑stage biotechnology company harnessing the power of the human immune system to develop transformative therapies for cancer and autoimmune disease. Using its proprietary DECODE™ platform—which maps the immune synapse between T cell receptors (TCRs) and their antigen targets—Repertoire translates unique biological insights into potent and targeted off‑the‑shelf immune medicines. The company integrates deep protein engineering expertise with artificial intelligence, powered by a proprietary DECODE database of over one billion TCR‑antigen interactions, to accelerate discovery and optimize drug candidates.

From its sites in Cambridge, Massachusetts and Zurich, Switzerland, Repertoire is advancing a pipeline of T cell‑targeted immunotherapies with the potential to address a broad range of cancers and autoimmune disorders. The company’s lead oncology program, RPTR-1-201, a TCR bispecific, has initiated a Phase 1/2 clinical trial across multiple solid tumor indications. Repertoire plans to advance additional TCR bispecific therapies into clinical trials over the next 12‑18 months.

In autoimmune disease, Repertoire is partnering with leading pharmaceutical companies to develop mRNA tolerizing therapies designed to selectively expand regulatory T cells and reset the immune system.

Repertoire was founded in 2019 by Flagship Pioneering and is supported by a strong investor base. The DECODE platform has been validated through four strategic partnerships with leading pharmaceutical companies—Bristol Myers Squibb, Genentech, Eli Lilly, and Pfizer—representing over $4.5 billion in disclosed total deal value and $185 million in upfront payments received to date.

We are seeking a detail‑oriented and collaborative Staff Accountant to join our growing Finance team. This is an excellent opportunity for an accounting professional who is eager to broaden their expertise, gain exposure to a wide range of accounting responsibilities, and develop into a Senior Accountant as they demonstrate increasing ownership, initiative, and leadership. In this role, you will support day‑to‑day accounting operations, play a key role in the monthly close process, and contribute to strengthening our financial infrastructure as the company continues to grow.

We are looking for a colleague who is excited to contribute to our collaborative culture and values working alongside teammates in our Cambridge office a minimum of three days per week.

• Assist with the timely completion of the month‑end close through the preparation of journal entries, account reconciliations, and period‑over‑period account fluctuation analyses.
• Perform the monthly cash reconciliation process.
• Maintain fixed asset, lease, and other current asset schedules.
• Assist with the monthly purchase order accrual process, collaborating with external vendors and internal business stakeholders, including FP&A.
• Collaborate with Accounts Payable to resolve vendor and billing issues.
• Coordinate weekly check runs and monitor accounts payable to ensure invoices are recorded, approved, and paid on time.
• Support the preparation of financial statement audits, tax compliance reporting, and other regulatory filings, as needed.
• Support the maintenance and implementation of internal controls, including identifying opportunities for process improvements and operational efficiencies within areas of responsibility.
• Ensure accounting records are complete, accurate, and maintained in accordance with U.S. GAAP and Company policies.
• Participate in special projects, systems enhancements, and continuous improvement initiatives as the Finance organization continues to grow.
• Perform other duties and special projects as assigned.

• Bachelor’s degree in accounting required.
• 2+ years of corporate and/or public accounting experience required.
• Experience with general ledger functions and the month‑end/year‑end close process; experience with consolidations of multiple subsidiaries, including international entities, is a plus.
• Relevant experience in the biotech or pharmaceutical industry preferred.
• Knowledge…