Senior Manager, Global Strategic Sourcing

Role Overview

The Senior Manager, Global Indirect Strategic Sourcing is responsible for leading and optimizing external spend across key G&A and Commercial category families. This role will own select subcategories within areas such as IT, Travel, Professional Services, Commercial, and External Workforce, representing a portion of an overall ~$500M and growing global spend. The position requires a dynamic, hands‑on sourcing leader with strong communication and influencing skills who can elevate sourcing value and partner effectively across G&A and Commercial functions.

This position is hybrid and will be primarily located in Cambridge, MA
.

• Develop and implement comprehensive global category strategies for specific Indirect categories with business objectives, risk mitigation, and total cost of ownership principles.
• Partner with cross‑functional stakeholders company‑wide to anticipate business needs and proactively shape sourcing strategies.
• Lead end‑to‑end sourcing initiatives, including RFx development, bid evaluations, negotiations, and contract execution.
• Identify, qualify, and manage strategic supplier relationships to ensure performance, innovation, compliance, and value delivery.
• Deliver year‑over‑year cost savings, cost avoidance, and value improvements through commercial negotiations, process efficiencies, and demand management.
• Continuously analyze market trends and spend data to identify opportunities for value generation and risk mitigation.
• Serve as the primary procurement partner for facilities, engineering, and real estate, influencing and advising on procurement best practices and strategic sourcing decisions.
• Facilitate supplier business reviews with stakeholders to align performance metrics, KPIs, and continuous improvement opportunities.
• Champion continuous improvement and procurement excellence within the category scope.
• Develop and implement sourcing strategy and action plans to support Alnylam's Supplier Diversity and Sustainability initiatives.
• Build strong relationships with business partners including Financial Planning and Analysis, Finance Operations, Legal, Compliance, Human Resources, and other peers within the GSS organization.

• Bachelor's degree required, in a technical discipline desired.
• Advanced degree (MBA/MS) or professional certifications (CPSM, CFM, MCR, QPCR) desired.
• 6+ years of strategic sourcing or procurement experience, ideally within biotech or pharmaceutical industries.
• Expertise in indirect category strategic sourcing.
• Demonstrated ability to develop and execute category strategies using TCO, market intelligence, and spend analytics.
• Track record of delivering measurable cost savings, operational efficiencies, and supplier performance improvements.
• Strong proficiency in sourcing and ERP tools (e.g., SAP, Ariba, Workday), with advanced Excel and PowerPoint skills.
• Skilled in leading RFx events, commercial negotiations, and contract lifecycle management.
• Proven ability to manage global suppliers through KPIs, SLAs, audits, and business reviews.
• Collaborative and business‑oriented mindset; effective at influencing cross‑functional stakeholders.
• Excellent verbal and written communication skills, with an ability to distill complex topics for senior audiences.
• Self‑starter who thrives in fast‑paced, mission‑driven biotech environments.
• Committed to continuous improvement, with a strong sense of accountability and adaptability.

#LI-MH1 #LI-Hybrid

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The pay range reflects the full‑time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short‑term incentive award (e.g., bonus or sales incentive) and an annual long‑term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well‑being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts…