Associate Director, Forecasting & Performance Analytics, Commercial Operations & Analytics

Who We Are

At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate.

Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built.

Agios is searching for a dynamic Associate Director, Forecasting & Performance Analytics to join our growing Commercial Operations & Analytics team. This role leads forecasting and national performance analytics across our marketed and pipeline portfolio, with a particular emphasis on rare and genetically defined diseases. It builds the demand, revenue, and long‑range models that anchor planning and the executive and board narrative, and owns the national performance reporting that shows how launches and in‑line products are tracking.

This is a hands‑on role for someone who can build rigorous, defensible models and translate them into clear recommendations for commercial leadership. The Associate Director partners closely with Commercial, Finance, Supply, and Portfolio Management and supports business development assessments.

• Build, maintain, and evolve operational, unit‑based forecasts across the portfolio – demand, revenue, and patient‑based models – including scenario planning and risk and opportunity assessments for multiple launches and in‑line products
• Develop and manage long‑range planning (LRP) forecasts in partnership with Commercial, Finance, and Corporate Strategy, clearly documenting assumptions, risks, and opportunities
• Select and apply the most appropriate forecasting approach for each question – epidemiology‑based, demand‑based, or analog‑based – and continuously strengthen forecasting best practices, tools, and processes
• Own national‑level commercial performance reporting and analytics, building and maintaining the KPI frameworks, dashboards, and scorecards that track launch and in‑line performance for brand, commercial, and executive audiences
• Surface emerging performance trends, likely drivers, and areas of opportunity by integrating secondary data, field intelligence, competitive signals, and market research
• Deliver ad hoc forecasting and analytics to support board meetings, earnings calls, and investor discussions
• Support business development and corporate strategy with market sizing, valuation inputs, and commercial forecasts for pipeline and partnering opportunities
• Guide the secondary analytics and primary research needed to validate forecast assumptions, model architecture, and patient populations
• Act as an internal consultant across Commercial, Finance, Market Access, Clinical, Supply, and Regulatory to support cross‑functional decision‑making
• Direct third‑party forecasting resources to extend capacity while maintaining quality and timelines

• 8+ years of experience in forecasting, commercial analytics, or performance reporting in the biopharmaceutical industry; bachelor’s degree required; advanced degree (e.g., MBA) preferred
• Strong forecasting and financial modeling skills, including dynamic Excel models; able to build, present, defend, and maintain operational and long‑range forecasts with a high degree of precision
• Strong knowledge of biopharmaceutical secondary data sources (e.g., specialty pharmacy, claims and longitudinal patient, sales, and payer data) and how to apply them to forecasting and performance analytics
• Experience designing and interpreting KPI frameworks, dashboards, and launch and in‑line performance reporting
• Experience in rare or genetically defined diseases, including in‑line and pipeline products, strongly preferred
• Experience supporting business development or licensing…