Chief of Staff | Program Management & Operations

Summary

Acoustica Bio is hiring a Chief of Staff to work directly with the Leadership and the Founder/CEO to drive execution across the company and help shape how we operate as we scale.

This is a rare opportunity to join Acoustica Bio at a pivotal moment, as we build a new paradigm in biologics formulation and drug delivery—enabling more accessible, scalable, and patient‑friendly therapies.

We are a venture‑ and NIH‑funded deep‑tech startup spun out of Harvard, building a proprietary platform that leverages physics‑first approaches to transform biologics manufacturing and delivery. Our technology enables ultra‑high‑concentration formulations for subcutaneous delivery, addressing fundamental challenges in viscosity, stability, and manufacturability.

This is not a traditional “support” role. The person in this position will serve as a force multiplier for the CEO and the team, operating at the intersection of execution, communication, and operation. You will help ensure that priorities are translated into action, that key initiatives move forward with clarity and urgency, and that the organization remains aligned as we grow.

We are looking for a team‑first operator with high ownership and exceptional communication skills—a person who enjoys bringing structure to complexity and is excited to play a central role in shaping the operations, trajectory, and culture of the company.

For the right candidate, this is an opportunity to step into a highly visible role with direct exposure to company‑building, decision‑making, and scaling a deep‑tech biotech startup.

• Translate company priorities into clear plans, timelines, and owners across R&D, partnerships, fundraising, and operations
• Track progress against key milestones (e.g., grant deliverables, technical programs, external collaborations) and ensure consistent follow‑through
• Refine or establish weekly meetings, planning cycles, tracking tools
• Identify risks, bottlenecks, and misalignment early, and proactively drive resolution

• Own key aspects of day‑to‑day operations, from coordinating across the team to running core workflows (vendors, finances, tools), supporting legal and administrative needs, and ensuring things get done end‑to‑end

• Help prioritize, coordinate, and prepare key decisions, meetings, and external interactions
• Reduce operational overhead and ensure focus on the highest‑impact initiatives

• Support preparation of materials for investors, partners, collaborators, and grant submissions
• Ensure clarity and alignment across the team by synthesizing complex discussions into actionable outcomes

• Take ownership of high‑priority initiatives that do not naturally fit within a single function
• Operate across scientific, operational, and business domains as needed

• Step in wherever needed to move the company forward, from high‑level planning to detailed execution

• 3–6+ years of experience in a startup or fast‑paced environment, in hands‑on roles such as Program Management, Business Operations, Strategy & Operations, Consulting, or similar
• Demonstrated experience directly driving cross‑functional initiatives end‑to‑end, with clear ownership of outcomes—not just coordination
• Outstanding communication skills, with the ability to synthesize complex information and present clearly to diverse audiences
• Strong organizational and program management skills, with an ability to track multiple priorities simultaneously without losing focus
• High level of ownership and accountability; able to independently drive work forward without constant direction
• Operate at all levels— from high‑level planning to hands‑on operational work
• Comfort working closely with senior leadership and external stakeholders
• Experience in biotech, life sciences, or deep‑tech startups is a plus, but not required

We’re looking for an operator and leader…