Global Asset Lead, Oncology Therapy Area, Research and Development

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Job Description Orion Pharma is currently seeking to recruit an experienced Global Asset Lead (GAL) to take end‐to‐end accountability for the strategic vision and successful delivery of a priority oncology program. In this pivotal role, you will lead a high‐performing Global Program Team (GPT) in a dynamic matrix environment, integrating the efforts of Clinical, Regulatory, CMC, Medical Affairs, and Commercial functions.

Your mission is to maximize the medical and commercial value of the asset from early transition (Phase 1/2) through global registration, launch, and long-term life cycle management. This role requires a balance of technical depth (scientific and clinical rigor) and business acumen (BD, portfolio strategy, and market dynamics).
** Key Responsibilities
**** 1. Integrated Development Plan (IDP) & Strategic Vision**
* ** Integrated Development Plan Ownership:
** Lead the creation and annual update of the
** Integrated Development Plan**, ensuring clinical, regulatory, technical, and commercial work streams are harmonized into a single, cohesive roadmap.
* ** Target Product Profile (TPP):
** Develop, refine and execute on the TPP and ensure all development activities are designed to achieve a competitive and differentiated label that meets both regulatory requirements and payer/market needs.
* ** Evidence Generation:
** Partner with Medical Affairs and Clinical to drive an integrated evidence generation strategy (including RWE and HEOR) to support global market access and reimbursement.
** 2. Matrix Leadership & Cross-Functional Liaison**
* ** Project Team Leader:
** Lead the GPT as the central decision-maker, ensuring that
** Clinical, CMC, Regulatory, Medical Affairs, and Commercial
** are aligned on the asset’s primary objectives.
* ** Functional Synergy:
** Serve as the primary liaison between technical R&D (CMC/Clinical) and downstream functions (Commercial/Market Access) to ensure the asset is "launch-ready" from a supply and value-proposition perspective.
* ** Matrix Leadership:
** Proactively manage cross-functional priorities, trade-offs, and resource constraints to ensure the program remains on track.
** 3. Governance, Risk & Portfolio Management**
* ** Governance Representative:
** Act as the lead presenter for the asset at Senior Executive Governance (e.g., Investment Committees, Portfolio Boards). Secure funding and alignment for major milestones (Phase 2/3 transitions).
* ** Decision Science:
** Establish clear **"Go/No-Go"
** decision points and objectively present data to governance to drive portfolio-level prioritization.
* ** Risk Mitigation & Scenario Planning:
** Lead formal risk assessments and develop robust contingency/back-up scenarios for clinical failures, regulatory shifts, or competitive market entries.
** 4. Life Cycle Management (LCM) & Value Maximization**
* ** Line Extensions:
** Strategize and execute the expansion of the asset into new indications, earlier lines of therapy, and novel combination regimens (e.g., IO combinations, ADC sequencing).
* ** Pediatric & Regional Strategy:
** Ensure the IDP includes global geographic considerations (e.g., China/Japan development) and mandatory pediatric investigation plans (PIP/PSP).
* ** Collaborations & Alliances:
** Lead collaborations with academic cooperative groups (e.g., ECOG, EORTC) and manage Joint Steering Committees (JSC) for co-development assets with industry partners.
** 5. Business Development (BD) & Strategic Initiatives**
* ** BD Technical Lead:
** Serve as the asset expert for due diligence on potential in-licensing opportunities that complement the asset’s core strategy.
* ** External Advocacy:
** Build and maintain high-level relationships with global Key Opinion Leaders (KOLs) and participate in strategic partnering/investor discussions.
* ** Competitive Intelligence:
** Continuously monitor the oncology landscape to adjust asset strategy in response to emerging "Standard of Care" shifts or competitor data readouts.
* Opportunity to work with talented and experienced scientists and assistants across Orion’s RnD.
* An exciting R&D pipeline and enthusiastic working environment with opportunities to use your strengths to…