Director, Strategy & Operations GI

Job Description

About the role:

The Director, Strategy & Operations reports directly to the SVP, Head of Gastrointestinal & Inflammation Business Unit and serves as a strategic advisor and operating partner to the GI² leadership team. This role drives the operating framework, governance, prioritization, and execution of key BU-wide strategic initiatives to enable effective decision-making, operational discipline, and cross-functional alignment across the business. The Director ensures visibility to critical priorities, risks, dependencies, financial considerations, and execution progress, while leading integrated planning and operational management for the Business Unit.

This is a hybrid role based in Cambridge, MA.

How you will contribute:

Serves as a strategic advisor and operating partner to the SVP, Head of GI², providing thought partnership on BU priorities, operating model effectiveness, strategic initiatives, budget considerations, and leadership team decision-making.

• Drives the GI²operating cadence,including leadership team agendas, governance forums, decision-making processes, follow-up actions, andintegrationof BUprioritiesintoUSBU executive planning and reporting.

• Leads the planning, coordination, and execution of BU-wide strategic initiatives and special projects, ensuring clear ownership, milestones, deliverables, and escalation pathways.

• Monitors progress against strategic priorities,identifying risks, dependencies, gaps, and opportunities;develops metrics, dashboards, and executive-level updates to enabletimelydecisions and course correction.

• Leads executive external engagement activities, partnering with cross-functional teams to execute congress and conference strategies, coordinateHCPand patient advocacy engagements, and oversee field visits that strengthen stakeholder relationships and support business priorities

• Partners with Finance and BU leaders to support budget planning, resource allocation, financial tracking, and effective management of investments across the GI² BU.

• Develops executive-level communications that translate business strategy, priorities, performance, and organizational updates into clear, consistent messaging for internal and cross-functional audiences.

• Builds strong cross-functional partnerships across USBU, Finance, HR, Communications, and other key functions to remove barriers, align stakeholders, and advance enterprise priorities.

• Leads, coaches, and develops direct reports, ensuring clear priorities, accountability, capability building, and effective delivery of strategy and operations support across the BU

Technical/Functional (Line) Expertise

• Demonstrated experience translating business priorities into actionable strategies, operating plans, and measurable execution outcomes.

• Proven ability to partner with commercial, medical, finance, HR, communications, and cross-functional teams to drive strategy implementation and operational improvements.

• Strong project management, financial acumen, analytics, reporting, and executive dashboard capabilities, including resource planning, budget tracking, and performance measurement.

Leadership

• Strong enterprise mindset with the ability to influence across a matrixed organization and align senior stakeholders around shared priorities.

• Demonstrated ability to lead through ambiguity, exercise sound judgment, and drive disciplined execution in a dynamic business environment.

• Provenpeopleleadership capability, including setting direction, coaching talent, building capability, and fostering accountability.

Decision-making and Autonomy

• Ability to manage multiple high-priority initiatives simultaneously whilemaintaininga clear view of strategic implications, risks, dependencies, and tradeoffs.
• Usessound judgment and business insight…